腹水超滤浓缩回输联合静脉输入人血白蛋白、利尿治疗顽固性腹水疗效观察  

Observation of curative effect of ultrafiltration and peritoneal reinfusion of ascites and vein auto-transfusion and human serum albumen diuresis treatment refractory ascites

作　　者：周辉[1] 杨树清[1] 刘君俊 沈金勇 

机构地区：[1]四川省巴中市中心医院,巴中636000

出　　处：《北方药学》2011年第5期64-65,共2页Journal of North Pharmacy

摘　　要：目的:评估腹水超滤浓缩回输联合输入人血白蛋白、利尿治疗顽固性腹水的临床疗效。方法:将我院2006～2010年收治的214例乙肝肝硬化腹水病例经基础治疗3～4天效果不好的78例,随机分为三组,第一组采用传统纠正低蛋白血症、利尿内科治疗;第二组采用单纯性腹水超滤浓缩回输治疗;第三组采用腹水超滤浓缩回输联合输入人血白蛋白、利尿治疗。分别观察三组症状缓解情况、并发症、腹围缩小及血浆白蛋白上升情况。结果:第三组在症状缓解、腹围缩小及血浆白蛋白上升情况均优于其他两组,在并发症方面第二、三组采用腹水超滤回输并发症发生均低于第一组。结论:腹水超滤浓缩回输联合输入人血白蛋白、利尿治疗,是目前治疗顽固性肝硬化腹水效果较好、安全的方法。Aims evaluate the clinical effect of ultrafiltration and peritoneal reinfusion of ascites and vein auto-transfusion and human serum albumen diuresis treatment refractory ascites.Methods During 2006 and 2010,we received 214 cases of hbv-liver cirrhosis ascites. After 3 or 4 days＇ basic treatment,there were 78 cases whose treatment effect was not obvious. We divided them into 3 groups by random distribution. We treated it by traditional correcting and diuresis medical treatment in the first group;We treated it by ultrafiltration and peritoneal reinfusion of ascites in the second group;We treated it by ultrafiltration and peritoneal reinfusion of ascites and vein auto-transfusion and human serum albumen diuresis treatment refractory ascites. We observed the 3 groups in symptom remission situation,complication,decrease of girth in the abdomen,serum albumen concentration respectively.Results The third group is better than the other groups in symptom remission situation,decrease of girth in the abdomen,serum albumen concentration. The second and third groups are lower than the first group in complication.Conclusion Ultrafiltration and peritoneal reinfusion of ascites and vein auto-transfusion and human serum albumen diuresis treatment is a kind of good and safe methods in treating refractory cirrhosis ascites.

关 键 词：乙肝 肝硬化 顽固性腹水 超滤浓缩 回输 

分 类 号：R575.2[医药卫生—消化系统]