肺癌的性别差异及机制  

Gender-associated Differences of Lung Cancer and Mechanism

作　　者：邢昕[1,2] 廖永德[1] 唐和孝[1] 陈广[1] 具晟[1] 游良琨[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院普胸外科,武汉430030 [2]湖北省中山医院心胸外科,武汉430033

出　　处：《中国肺癌杂志》2011年第7期625-630,共6页Chinese Journal of Lung Cancer

摘　　要：肺癌是全球发病率、死亡率最高、治疗效果差的恶性肿瘤。肺癌在流行病学、病理类型、疗效和预后、甚至发病机制等多方面均表现出明显性别差异。对这些差异的深入剖析能更好地认识男女性别肺癌各自的特点,为肺癌防治采用不同的性别化措施提供新线索和思路;而对导致性别差异的具体机制进行深入研究,有助于阐明肺癌的发病机制。Lung cancer has been viewed as the most common malignant cancer with high incidence, mortality and poor survival all over the world. A lot of investigations indicated there are significant gender-associated differences in lung cancer in several characteristics such as epidemiology, pathology, clinical outcome and prognosis. The insight into these differ- ences may help to clarify the gender-associated characteristics of lung cancer, and to drawn out new approach for treatment and prevent of lung cancer depending on gender-associated characteristics. Furthmore, study on mechanism of gender-associated characteristics may even help to illuminate the pathogenesis of lung cancer.

关 键 词：肺肿瘤 性别 差异 

分 类 号：R734.2[医药卫生—肿瘤]