多发性硬化患者合并症临床分析  

Complications in Patients with Multiple Sclerosis

作　　者：张先龙[1] 唐玉兰[2] 肖凯文[2] 刘波[2] 

机构地区：[1]湖南省娄底市中心医院神经内科,417000 [2]广西医科大学第一附属医院神经内科

出　　处：《中国全科医学》2011年第20期2306-2307,共2页Chinese General Practice

摘　　要：目的探索多发性硬化(MS)合并症的发生、类型、相互作用及其对预后的影响。方法回顾性分析临床确诊的254例MS住院患者的临床资料,总结其合并症的发生情况、治疗及转归。结果 254例MS患者中有72例合并一种或以上其他疾病;其中合并超敏性疾病7例、其他自身免疫性疾病(AID)33例、寄生虫感染4例、免疫功能低下性疾病15例。有合并症MS组患者入院时、出院时的神经功能缺损评分均高于无合并症MS患者,差异有统计学意义(P<0.05)。结论 MS患者可以合并超敏性、自身免疫性、免疫低下性疾病等;充分认识MS的合并症具有重要意义。Objective To explore the occurrence,types,interactions,and prognostic impact of complications in patients with multiple sclerosis.Methods Clinical data of 254 cases of clinically diagnosed MS patients were analyzed retrospectively to summarize the occurrence,treatment,and outcomes of MS complications.Results Of the 254 MS cases,72 showed one or more complications,of which 7 were complicated with hypersensitivity diseases,33 with autoimmune diseases,4 with parasitic infections,15 with immune dysfunction diseases.All MS patients with complications showed higher neurological deficit scores than those without complications at admission and discharge,with significant differences（P0.05）.Conclusion Complications in MS patients involve hypersensitivity,autoimmune,and other immunosuppressive diseases.It is of great importance to fully understand complications among MS patients.

关 键 词：多发性硬化 合并症 自身免疫性疾病 

分 类 号：R744.51[医药卫生—神经病学与精神病学]