正常小儿中脑导水管区脑脊液流动的MRI研究  

MRI study of cerebrospinal fluid flow in the cerebral aqueduct in normal children

作　　者：岳云龙[1] 刘洪亮[1] 金延方[1] 龚建伟[2] 吴晓华[3] 张奇瑾[1] 李滨[1] 胡志强[4] 

机构地区：[1]首都医科大学附属北京世纪坛医院放射中心,100038 [2]北京理工大学机械与车辆工程学院,100081 [3]首都医科大学附属北京友谊医院放射科,100050 [4]首都医科大学附属北京世纪坛医院神经外科,100038

出　　处：《中国微侵袭神经外科杂志》2011年第7期303-306,共4页Chinese Journal of Minimally Invasive Neurosurgery

基　　金：北京世纪坛医院科研基金(编号:2008-16;2009-23)

摘　　要：目的测量正常小儿中脑导水管区脑脊液流速、流量。方法应用MRI对15例健康小儿志愿者行中脑导水管区磁共振相位对比电影成像(Cine PC MRI),测量并计算中脑导水管脑脊液收缩期最大流速(MSV)、舒张期最大流速(MDV)、平均流率(AFR)及1个心动周期脑脊液搏动量(SV)、净流量(NV)。比较不同性别之间各参数是否存在差异。结果正常小儿MSV和MDV分别为(-3.73±0.81)cm/s及(3.72±1.09)cm/s,AFR为(7.61±2.84)ml/min;1个心动周期的SV及NV分别为(40.53±13.89)μl及(-8.89±5.09)μl。各参数在不同性别之间差异均无统计学意义(P>0.05)。结论建立MRI对正常小儿中脑导水管区脑脊液流速、流量正常值,为进一步定量分析小儿导水管区脑脊液循环障碍性疾病提供帮助。Objective To measure the velocity and rate of cerebrospinal fluid（CSF） flow in cerebral aqueduct of normal children.Methods Cine phase-contrast magnetic resonance imaging（Cine PC MRI） was performed in cerebral aqueducts of 15 normal children.The CSF parameters such as maximal systolic velocity（MSV）,maximal diastolic velocity（MDV）,average flow rate（AFR） and stroke volume（SV） and net volume（NV） per cardiac cycle were measured and recorded.The parameters were compared between male and female.Results The MSV,MDV and AFR was-3.73±0.81cm/s,3.72±1.09cm/s and 7.61±2.84ml/min respectively in normal children.The SV and NV per cardiac cycle was 40.53±13.89μl and-8.89±5.09μl respectively in normal children.There were no statistical significance in the difference of every parameters between males and females（P0.05）.Conclusions The normal values of cerebral aqueduct CSF flow in normal children are established by MRI,which provides assistance for quantitatively analyzing the diseases of CSF circulatory disturbance in cerebral aqueduct area in children.

关 键 词：脑脊液 脑导水管 磁共振成像 电影 小儿 

分 类 号：R445.2[医药卫生—影像医学与核医学]