甲状腺功能亢进症患者血清IV型胶原测定的临床意义  

A DETECTION OF DETERMINING COLLAGEN IV IN SERUM IN PATIENTS WITH HYPER THYROIDISM

作　　者：缪鹰 陈东平 乔小倪 

机构地区：[1]浙江省丽水地区医院,323000

出　　处：《河北医学》1999年第12期12-14,共3页Hebei Medicine

摘　　要：目的：探讨甲状腺功能亢进症（甲亢）患者早期肝损坏的程度。方法：采用全自动发光免疫法测定１３８ 例患者血清ＩＶ 型胶原，同时检测ＦＴ３ 、ＦＴ４ 、ＡＬＴ。结果：甲亢伴ＡＬＴ增高者，ＩＶ 型胶原值为正常人２ 倍以上，且随ＦＴ３、ＦＴ４ 值升高而升高。结论：甲亢患者早期已有肝脏损伤，并可能已有肝纤维化。Objective:To detect the extent of damage in liver in patients with heperthyroidism.Method:Collagen IV was determined by auto immunofluorescence,as were FT 3,FT 4 and ALT at the same time in 138 cases.Result:The level of collagen IV in the cases is as more twice as in normal contrast,and increases with FT 3 ,FT 4.Conclusion:There is injury and fibrosis in liver in patients with heperhyroidism.

关 键 词：甲状腺机能亢进 IV型胶原 肝纤维化 诊断 

分 类 号：R575.204[医药卫生—消化系统] R581.106[医药卫生—内科学]