调节性T细胞与肿瘤  

Regulatory T cells and tumor

作　　者：杨继元[1] 杜伟[1] 

机构地区：[1]长江大学附属第一医院肿瘤科,荆州434000

出　　处：《国际肿瘤学杂志》2011年第7期496-498,共3页Journal of International Oncology

摘　　要：调节性T细胞是具有免疫抑制功能的T细胞亚群，在维持机体免疫平衡和自身免疫耐受中起重要作用，最新研究表明，FOXP3^＋CD25^＋CD4^＋调节性T细胞在各种肿瘤患者的外周血与肿瘤组织内大量表达，并且与肿瘤发生、发展及预后有明显的关系。Regulatory T ceils are a specialized subpopulation of T lymphocytes that play important roles in immunosuppression, maintaining immune balance and self-immune tolerance. The latest researches show that not only that FOXP3^＋CD25^＋CD4^＋ regulatory T ceils （Tregs） are expressed in tumor tissues and peripheral blood of patients of various forms of cancers, Tregs also participate in the occurrence, development and prognosis of tumors.

关 键 词：T淋巴细胞 调节性 肿瘤 

分 类 号：R730.2[医药卫生—肿瘤]