内外联合照射剂量计算方法的研究  

Development and research on the voxelized dose program based on AAPM TG-43 for the brachtherapy combined with EBRT

作　　者：王彬冰[1] 狄小云[1] 潘林飞[1] 毛仙芝[1] 陈维军[1] Anupama HA 

机构地区：[1]浙江省肿瘤医院放射物理室,杭州310022 [2]Department of Medical Physics and Biomedical Engineering, Gono University Dhaka, Bangladesh

出　　处：《中华放射肿瘤学杂志》2011年第4期340-344,共5页Chinese Journal of Radiation Oncology

摘　　要：目的基于TG-43U1号报告剂量算法开发体元化的铱-192后装剂量计算程序，通过该程序将两个不同治疗计划系统的内外照射计算结果叠加、计算并显示总剂量分布。方法在开发的后装铱-192刘量计算程序中，根据Nucletron Plato治疗计划系统中读取的后装治疗计划的治疗信息（放射源强度、驻留位置、驻留时间等），重建出参照ADAC治疗计划系统坐标的后装源驻留位置，并重新计算后装治疗计划的三维剂量分布。计算结果经开发的程序转换并输入到ADAC计划系统，在ADAC中重建后装剂量分布并和ADAC外照射计划的剂量分布结果相叠加。结果根据TG-43U1号报告算法编写的程序剂量计算结果和Nucletron的Plato治疗计划系统得到的计算结果完全一致，误差〈0．1％。同时，该计算结果可以在ADAC计划系统上和其他外照射计划进行叠加。结论笔者编写的铱-192后装剂量计算程序能使不同治疗计划系统的内外照射计算结果叠加，有一定的临床使用价值。Objective To develop a brachtherapy （BT） dose calculation program based on AAPM TG-43UI formula. With this program we can combine the dose result of external beam radiotherapy （EBRT） and BT together which is calculated by the different treatment planning TPS. Methods BT treatment data, such as source parameter, dwelling position and dwelling time, are retrieved from Nucletron Plato planning system and converted to ADAC planning system coordinate. The BT 3D dose distribution is re-calculated as well. Then the 3D dose distribution is exported to ADAC planning system. In that way, ADAC planning system can display either the EBRT dose or the BT dose and the combined dose can be calculated, displayed and evaluated as well. Results BT dose calculation result of our program which based on AAPM TG-43UI formula is identical with which of Plato （ 〈 0. 1% ）. Furthermore, the BT dose can be transfer to the ADAC easily and the dose distributions of combined therapy can be merged in ADAC, Conclusions Our program can be used to combine the dose result of EBRT and BT from different TPS.

关 键 词：内外联合照射 TG--43U1号报告 剂量学 

分 类 号：R730.55[医药卫生—肿瘤]