MRI靶区定位在不张型肺癌^125I粒子植入治疗中的应用  

The Value of MRI In Orientation of the Masses in Central Bronchial Carcinoma Accompanied with Atelectasis during Treatment with Interstitial Implantation of ^125I Seeds

作　　者：邢刚[1] 柴树德[2] 郭德安[1] 廉宗激[3] 

机构地区：[1]天津市泰达医院放射科,天津300457 [2]天津医科大学第二医院胸外科 [3]天津医科大学第二医院放射科

出　　处：《实用放射学杂志》2011年第7期1021-1024,共4页Journal of Practical Radiology

摘　　要：目的 探讨中央型肺癌伴阻塞性肺不张125I粒子植入治疗中MRI对肿瘤靶区的定位价值.方法 选取34例CT平扫无法区分出肺不张中瘤体的中央型肺癌患者,行胸部MRI检查.将MRI上可以清晰显示中央型肺癌瘤体与不张肺组织界限的MR图像与其对应的CT图像分别输入TPS系统,进行术前粒子植入区体积及放射剂量学估算,比较二者差异.本组数据采用t检验,P〈0.05确定为差异有显著意义.结果 34例中,有29例（85.3%）MRI可以区分瘤体与不张的界限,3例MRI界限模糊,2例MRI无法区分界限.29例中MRI勾画的肿瘤靶区总面积较CT靶区缩小15.53%,节省粒子14.81%（P〈0.05）.结论 中央型肺癌伴阻塞性肺不张125I粒子植入治疗中MRI对肿瘤靶区的定位具有重要价值,有效地保证了125I放射性粒子植入治疗肺癌的疗效和辐射安全性.Objective To discuss the value of MRI in orientation of the masses in central bronchial carcinoma accompanied with atelectasis during the therapy with interstitial implantation of ^125I seeds. Methods 34 cases with central bronchial carcinoma were examined by MRI, of which the masses could not be distinguished from the atelectasis by CT. MR images in which the margins between the masses and atelectasis distinguished, and CT images corresponding to MR imges were inputed into the TPS respectively for evaluation of the volume of masses and radiation dose preoperation comparatively showed on CT and MRI using t test. Results Of the 34 cases, the bounds between the masses and atelectasis were demonstrated clearly by MR imaging in 29 cases,faintly in 3 cases and failingly in 2 cases. The target whole areas of the masses showed by MRI reduced of 15. 53% compared with CT and the seeds reduced of 14.81% totally（P〈0.05）. Conclusion MRI plays an important role in the orientation of the masses in central bronchial carcinoma accompanied with atelectasis,which can help to assure the operational safe and available in treatment of the tumors with implantation of ^125I seeds.

关 键 词：肺 肺癌 磁共振成像 放射性核素 ^125I粒子 

分 类 号：R734.2[医药卫生—肿瘤] R563.4[医药卫生—临床医学]