影响早产和痉挛型脑性瘫痪发生的多因素分析  

Factors of preterm birth and spastic cerebral palsy

作　　者：马磊[1] 金岚[2] 段军[1] 唐久来[1] 

机构地区：[1]安徽医科大学第一附属医院小儿神经康复中心,合肥230032 [2]合肥市妇幼保健院,230031

出　　处：《安徽医学》2011年第7期886-888,共3页Anhui Medical Journal

基　　金：安徽省教育厅自然科学研究项目(项目编号:2006KJ091A)

摘　　要：目的探讨影响早产及痉挛型脑性瘫痪发生的因素。方法采用病例对照研究设计,对265名脑瘫儿童和272名正常儿童的性别、出生体质量、出生胎龄、脑瘫类型、孕母年龄、分娩史、文化程度和经济状况等调整后进行非条件Logistic回归分析。结果在早产儿童中,经济状况中等及以上、文化程度较高及出生体质量<2.5 kg等具有统计学意义(P<0.05);痉挛型脑性瘫痪儿童中,女童、经济状况中等及以上、出生胎龄<32周、出生体质量>4 kg等具有统计学意义(P<0.05)。结论早产受社会因素的影响,经济状况中等及受教育程度较高可能是避免早产的因素。Objective To explore the factors of preterm birth and spastic cerebral palsy.Methods A case-control study was carried out.After controlling for sex,birth weight,gestational age,type of cerebral palsy,age of pregnant mother,birth history,economic status and education background in 265 cerebral palsy children and 272 controls with uniformed signed questionnaires,Unconditional Logistic regression analysis was performed to screen each variable.Results Middle and higher economic status,higher education background and birth weight（2.5 kg） had significant differeences in preterm birth children（P0.05）,while female children,middle and higher economic status,gestational age（32 weeks） and birth weight（4 kg） had significant differences in spastic cerebral palsy children（P0.05）.Conclusion Preterm birth is affected by socio-economic status,and moderate economic status may be factors of preventing preterm.

关 键 词：早产 痉挛型脑性瘫痪 多因素 

分 类 号：R742.3[医药卫生—神经病学与精神病学]