盐酸米诺环素软膏与甲硝唑药膜治疗牙周脓肿的疗效分析  

Analysis of Curative Effect of Periodontal Abscess Treated by Periocline and Metronidazole Residue

作　　者：袁贤君[1] 吴凡[1] 袁贤琳 任宏伟[1] 

机构地区：[1]广州开发区医院口腔科,广州510730 [2]广州市中医院药剂科,广州510130

出　　处：《中国医药导刊》2011年第6期1020-1020,1022,共2页Chinese Journal of Medicinal Guide

摘　　要：目的:探讨盐酸米诺环素软膏与甲硝唑药膜治疗牙周脓肿的疗效。方法:将80例牙周脓肿患者随机分为治疗组及对照组,对照组患者使用甲硝唑药膜,治疗组在对照组基础上加用2%盐酸米诺环素软膏。结果:经过治疗,治疗组总有效率为95.0%,显著高于对照组的70.0%,治疗后,两组患者的PLI、SBI、PD、MD与治疗前比较有显著改善,治疗组改善更显著,以上差异均无统计学意义(P<0.05)。在用药过程中,两组均未见有明显不良反应。结论:使用盐酸米诺环素软膏与甲硝唑药膜治疗牙周脓肿,二者联用具有协同作用,用药少、局部药物浓度高、避免了全身应用抗生素带来的不良反应、作用持久、患者依从性高。Objective： To analyse the curative effect of periodontal abscess treated by periocline and metronidazole residue. Methods： To randomly divide 80 periodontal abscess patients into curative group and comparision group, the patients in comparision group were treated only by metronidazole residue, while the patients in curative group were treated by metronidazole residue and 2% periocline. Results：After treatment, the effective rate in curative group is 95% which is much higher than the effective rate of comparision group （70%）. After treatment, the PLI, SBI, BD,MD of all the two group patients have improvement, curative group have more improvement, but the difference has no statistics meaning（P〈0.05）. During the treatment, there is no adverse reations in the two groups. Conclusions：When using periocline together with metronidazole residue to treat periodontal abscess, they will have synergism effect, less medicine, better concentration, avoid the adverse reation caused by antibiotics applied to the whole body, longer effect, better Treatment compliance, worth of popularizing.

关 键 词：盐酸米诺环素软膏 甲硝唑药膜 牙周脓肿 

分 类 号：R781.42[医药卫生—口腔医学]