复方苦参注射液联合常规灌肠治疗溃疡性结肠炎的疗效对比观察  

Clinical Study of Complex Lightyellow Sophora Root Injections with Routine Enema for Ulcerative Colitis

作　　者：田江[1] 李丹[1] 葛亮[1] 程伟[1] 徐永建 TIAN Jiang;LI Dan;GE Liang;CHENG Wei;XU Yongjian(Department of Gastroenterology,the Shihezi City People’S Hospital of Xinjiang Uygur Autonomous Region,Shihezi 832000,China;The Shihezi Center for Disease Prevention and Control,Shihezi 832000,China)

机构地区：[1]新疆维吾尔自治区石河子市人民医院消化科,新疆石河子832000 [2]新疆维吾尔自治区石河子市疾病控制中心,新疆石河子832000

出　　处：《中国现代医生》2011年第20期77-78,共2页China Modern Doctor

摘　　要：目的探讨复方苦参注射液联合常规灌肠治疗溃疡性结肠炎的临床疗效。方法选择2009年1月~2011年2月就诊的轻、中度活动期远段UC患者32例,随机分为治疗组17例,复方苦参注射液20mL加入生理盐水250mL中,静脉滴入,每日一次,联合甲硝唑0.4g+地塞米松10mg+生理盐水100mL混合摇匀,每晚睡前保留灌肠,10d为一个疗程;对照组15例仅使用常规保留灌肠法。结果治疗组和对照组总有效率分别为88.2%和64.3%,两组有明显差异(P<0.01)。结论复方苦参注射液联合常规灌肠治疗溃疡性结肠炎疗效确切,建议进一步了解此药的作用机制,做临床长期效果观察。Objective To investigate the clinical significance of complex lightyellow sophora root injection combined with conventional enema for ulcerative colitis.Methods 32 patients were randomized to treatment group in17 cases,the complex lightyellow sophora root injection in 20mL was added to 250mL normal saline,the intravenous infusion,once a day,and combined with metronidazole 0.4g+dexamethasone 10rag+NS 100mL were mixed,The retention enema before sleep was a course of treatment for 10 days,the control group in 15 cases were only used conventional retention enema.Results The total effective rate of the treatment group and control group were discerned 88.2%and 64.3%,with significantly different(P〈0.01).Conclusion Combine complex lightyellow sophora root injections with routine enema for ulcerative colitis were surely therapeutic effect,it is recommended to further understand the mechanism of the drug,the long-term effects of clinical was observed.

关 键 词：复方苦参注射液 溃疡性结肠炎 免疫调节 

分 类 号：R574.62[医药卫生—消化系统]