海岛居民肝癌危险因素的病例对照研究  

A Casecontrol Study on the Risk Factors of Primary Liver Cancer Among an Island Citizens

作　　者：张扬[1,2] 陈坤[1,2] 刘希永 朱益民[1,2] 朱永平 许朝宗[1,2] 陈建辉 

机构地区：[1]浙江医科大学流行病教研室 [2]浙江省洞头县卫生局

出　　处：《中国慢性病预防与控制》1999年第3期119-121,共3页Chinese Journal of Prevention and Control of Chronic Diseases

摘　　要：应用１∶３配比病例对照研究，了解浙江省海岛肝癌高发区洞头县原发性肝癌发病的危险因素，发现海岛居民肝癌发病与食用被污染甲壳类海产品和乙型肝炎病毒感染及心理等因素有较密切关系，提示少食甲壳类海产品，预防肝炎，多食绿色食品，保持乐观的人生态度可能有助于降低肝癌发病率。Incidence rate of primary liver cancer(PLC) in Dongtou county was much higher than in many other areas of China. Objective: To investigate the risk factors of PLC in the island citizens of Dongtou county,Zhejiang province. Methods: 90 PLC patients and 270 matched controls were interviewed in this investigation using a 13 casecontrol study. Results: The results confirmed the positive relationship between the history of eating dry or fresh mantis shrimp,fresh shrimp and PLC.The history of hepatitis B virus infection might also be an important factor for the incidence of PLC,and psychological factors might have an association with PLC,an increase in fruit intake (apple,orange) was beneficial to prevention of PLC. Conclusion:Z]This implied that the combined effects of some crustaceans intake and HBV infection need further investigation.

关 键 词：病例对照研究 肝癌 甲壳类海产品 危险因素 HBV 

分 类 号：R735.702[医药卫生—肿瘤]