引导组织再生术诱导兔下颌骨正中缝骨融合的研究  

Induction of osteointegration of rabbit mandibular central fissure with guided tissue regeneration

作　　者：徐欣[1] 杨丕山[1] 马跃[1] 孙善珍[1] 李茜[1] 王继同 

机构地区：[1]山东医科大学附属口腔医院,济南50012

出　　处：《上海口腔医学》1999年第4期193-194,共2页Shanghai Journal of Stomatology

基　　金：山东省卫生厅科研基金!9751

摘　　要：目的观察引导组织再生术诱导发育性骨裂隙骨再生融合的作用，为引导组织再生术在唇腭裂骨性裂隙修复中的应用提供实验依据。方法将国产聚四氟乙烯膜盖于兔下颌骨正中缝唇舌两侧，通过放射和病理检查，观察骨缝融合的情况。结果引导组织再生术能在4周左右诱导骨裂隙完全骨融合。结论引导组织再生术是修复骨性裂隙的有效方法，有可能用于齿槽裂、跨裂的骨性修复。Objective To observe the effect of guided tissue regeneration (GTR ) on induction of ostegenesis in developmental bone clefts,and provide a basis for the use of GTR to repair bony clefts in cleft lip and palate patients. Methods The e-PTFE membrane was placed on the labial and lingual sides of the rabbit mandibular central fissure. A radiological and pathological study was performed to determine the healing of the fissure integration. Results The results showed that the bony cleft was completely integrated 4 weeks after placement of the barrier membrane-.Conclusions GTR is an effective approach to reconstruct bony cleft ,and is likely to be used in repair of alveolar cleft and cleft palate.

关 键 词：齿槽裂 引导组织再生 骨融合 

分 类 号：R782.23[医药卫生—口腔医学]