恶性肿瘤患者无症状肺动脉栓塞检出率和相关风险因素分析  

Asymptomatic pulmonary embolism detected by CT in patients with malignant tumor:analysis of prevalence and risk factors

作　　者：万芸[1] 彭振鹏[2] 周旭辉[2] 李向民[2] 

机构地区：[1]广东省中医院放射科,510020 [2]中山大学附属第一医院放射科,510080

出　　处：《新医学》2011年第7期440-443,共4页Journal of New Medicine

基　　金：广东省自然科学基金(8151008901000210)

摘　　要：目的:探讨恶性肿瘤患者肺动脉栓塞(PE)发生率,以及肿瘤类型、远处转移、治疗方式、住院等风险因素对PE发生率的影响。方法:回顾性分析广东省中医院2008年1月-2009年12月收治的486例恶性肿瘤患者的胸部CT增强扫描资料,统计患者无症状PE的检出率,对不同性别、不同肿瘤类型,接受手术、化学治疗、放射治疗患者与未接受手术、化学治疗、放射治疗的患者的PE发生率进行比较。结果:18例患者检出PE,发生率为3.7%,男、女性肿瘤患者PE发生率比较差异无统计学意义,不同类型肿瘤PE发生率比较差异无统计学意义(P﹥0.05);肿瘤远处转移、接受放射治疗的恶性肿瘤患者PE发生率与无肿瘤远处转移、未接受放射治疗患者比较,差异无统计学意义,但近3个月内接受手术、化学治疗者PE发生率高于未接受手术、化学治疗者(P﹤0.05)。结论:对近期(3个月内)内接受手术、化学治疗的恶性肿瘤患者,临床需要密切监测,防范PE发生及其不良后果的可能。Objectives： To evaluate the prevalence and risk factors of pulmonary embolism （PE） in patients with malignant tumor. Methods： Data of 486 patients with malignant tumor, who received multi-detector thoracic CT during January 2008 to December 2009, were retrospectively reviewed. The incidences of PE in the patients with or without surgery, chemotherapy, or radiotherapy were analyzed. Results： PE was detected in 18 patients （3.7%）. There was no significant difference in PE prevalence between female and male patients, or among different typings of tumors （ P 〉 0. 05 ）. Meanwhile, there was no significant difference in PE prevalence between the patients with and without distant metastasis, or between patients with and without chemotherapy （ P 〉 0. 05 ）. How- ever, significantly higher risk of PE was revealed in patients received surgery or chemotherapy in the last 3 months than that in those did not （P 〈 0. 05 ）. Conclusion： Patients with malignant tumor who received surgery or chemo- therapy recently should be monitored for PE.

关 键 词：恶性肿瘤 肺动脉栓塞 发生率 流行病学 

分 类 号：R730.4[医药卫生—肿瘤]