喉神经内分泌癌2例及文献复习  

Laryngeal neuroendocrine carcinoma:Report of two cases with literature review

作　　者：伍丽娟[1] 范畴[1] 余良虎[1] 马俊[1] 

机构地区：[1]皖南医学院附属弋矶山医院耳鼻咽喉-头颈外科,安徽芜湖241001

出　　处：《皖南医学院学报》2011年第4期303-305,共3页Journal of Wannan Medical College

摘　　要：目的:探讨喉神经内分泌癌的诊断和治疗。方法:回顾分析我科收治的2例喉神经内分泌癌,其中1例行全喉切除加颈淋巴结清扫术,1例行喉部病灶切除,未行颈淋巴结清扫术。结果:第1例术后随访2年无复发;第2例术后1月症状复发,拒绝治疗于半年后死亡。结论:喉神经内分泌癌是一种发病率低、原发于喉部的特殊类型癌,正确的诊断有赖于临床特点、组织病理学、免疫组化检查。不同病理亚型的喉神经内分泌癌的治疗方法及预后是不同的。Objective：To investigate the diagnosis and treatment of neuroendocrine carcinoma of larynx.Methods：Two cases of laryngeal neuroendocrine carcinoma were analyzed retrospectively.One case received total laryngectomy with neck dissection and the other was treated with removal of the laryngeal lesions without neck dissection.Results：The first patient was found recurrence-free during 2 years of follow-up,and the second relapsed after one month of the surgery and was dead six months later as a result of refusal of management.Conclusion：Laryngeal neuroendocrine carcinoma is a rare case primarily developed in larynx with specific features.Accurate diagnosis comes from clinical characteristics,histopathologic appearance and immunohistochemical findings.The prognosis will differ a lot concerning treatment of dissimilar subtypes of this carcinoma.

关 键 词：喉神经内分泌癌 诊断 治疗 

分 类 号：R739.65[医药卫生—肿瘤]