A Rapid Synthesis of Pyranoid Glycals Promoted by β-Cyclodextrin and Ultrasound  

作　　者：赵晋忠 邵华武 武鑫 史少静 

机构地区：[1]Shanxi Agricultural University, Taigu, Shanxi 030801, China [2]Natural Products Research Center, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, Sichuan 610041, China

出　　处：《Chinese Journal of Chemistry》2011年第7期1434-1440,共7页中国化学（英文版）

摘　　要：A convenient and environmentally benign procedure for the synthesis of glycals from glycosyl bromides with very low zinc dust loading （1.5 equiv.） is described. The process is activated by β-cyclodextrin and ultrasound. Based on 19 samples, this method has been demonstrated to be highly effective for a broad range of glycosyl bromides, including acidor base-sensitive and disaccharide glycosyl bromides. A yield of 85%--96% of glycals was obtained.A convenient and environmentally benign procedure for the synthesis of glycals from glycosyl bromides with very low zinc dust loading （1.5 equiv.） is described. The process is activated by β-cyclodextrin and ultrasound. Based on 19 samples, this method has been demonstrated to be highly effective for a broad range of glycosyl bromides, including acidor base-sensitive and disaccharide glycosyl bromides. A yield of 85%--96% of glycals was obtained.

关 键 词：ULTRASOUND Β-CYCLODEXTRIN GLYCAL znic glycosyl bromide CARBOHYDRATE 

分 类 号：TQ424.25[化学工程] O636.12[理学—高分子化学]