GLYCAL

作品数:7被引量:4H指数:1
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相关机构:台湾大学更多>>
相关期刊:《Journal of Chinese Pharmaceutical Sciences》《Chinese Journal of Chemistry》《Chinese Journal of Natural Medicines》《复旦学报(自然科学版)》更多>>
相关基金:国家自然科学基金中国博士后科学基金高等学校学科创新引智计划河北省自然科学基金更多>>
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C-Aryl Glycosylation via Interrupted Pummerer Rearrangement
《Chinese Journal of Chemistry》2023年第21期2843-2847,共5页Jiagen Li Xuefeng Jiang 
The authors are grateful for financial support provided by NSFC(22125103and21971065);STCSM(22JC1401000,20xD1421500 and 20JC1416800);the Fundamental Research FundsfortheCentral Universities.
C-aryl glycosides are an important kind of carbohydrate derivatives for drug discovery,due to their distinctive attributes of resistance to hydrolysis from enzymes.Herein,C-aryl glycosylation was established for the s...
关键词:GLYCAL GLYCOSYLATION Interrupted pummerer REARRANGEMENT SULFOXIDE Carbohydrates C-GLYCOSIDES Drug discovery 
Chemical synthesis of a synthetically useful L-galactosaminuronic acid building block被引量:1
《Chinese Journal of Natural Medicines》2022年第5期387-392,共6页QIN Chun-Jun HOU Hong-Li DING Mei-Ru QI Yi-Kuan TIAN Guang-Zong ZOU Xiao-Peng FU Jun-Jie HU Jing YIN Jian 
supported by the National Natural Science Foundation of China(Nos.22077052,21877052,21907039);the China Postdoctoral Science Foundation(2020M681487);the National Key R&D Program of China(2020YFA0908304);the Natural Science Foundation of Jiangsu Province(BK20180030,BK20190575);the National First-class Discipline Program of Light Industry Technology and Engineering(LITE2018-14);the 111 Project(111-2-06);the Open Project of Key Laboratory of Carbohydrate Chemistry and Biotechnology(Jiangnan University),Ministry of Education(KLCCB-KF202005);the Natural Science Foundation of Xuzhou(KC19154).
Most bacterial cell surface glycans are structurally unique, and have been considered as ideal target molecules for the developments of detection and diagnosis techniques, as well as vaccines. Chemical synthesis has b...
关键词:L-galactosaminuronic acid Chemical synthesis Orthogonal protection Glycal addition C6 oxidation 
Improvement of Kdo’s efficient large-scale chemical synthesis method
《Journal of Chinese Pharmaceutical Sciences》2022年第2期97-107,共11页Ao Sun Zipeng Li Ting Liu Xiangbao Meng Shuchun Li Zhongjun Li 
National Natural Science Foundation of China(Grant No.81930097,21977005)。
Kdo residues are widely distributed in bacteria.They are components of bacterial lipopolysaccharide(LPS)and capsular polysaccharides,which can be recognized by the human adaptive immune system,and have great potential...
关键词:KDO Chemical synthesis 1 5-Lactone GLYCAL 
A Glycal Approach to the Synthesis of Pregnane Glycoside P57被引量:3
《Chinese Journal of Chemistry》2018年第11期1007-1010,共4页Chao Liu Yuyong Ma Chengfeng Pei Wei Li Biao Yu 
A Rapid Synthesis of Pyranoid Glycals Promoted by β-Cyclodextrin and Ultrasound
《Chinese Journal of Chemistry》2011年第7期1434-1440,共7页赵晋忠 邵华武 武鑫 史少静 
A convenient and environmentally benign procedure for the synthesis of glycals from glycosyl bromides with very low zinc dust loading (1.5 equiv.) is described. The process is activated by β-cyclodextrin and ultras...
关键词:ULTRASOUND Β-CYCLODEXTRIN GLYCAL znic glycosyl bromide CARBOHYDRATE 
Synthesis of Novel Fuctionalized Glycosides Based on 1,3-Dipolar Cycloaddition
《复旦学报(自然科学版)》2007年第5期585-,共1页Li Xiao-liu, Zhang Ping-zhu, Wang Yan-po, Chen Hua(Department of Chemistry, Laboratory of Chemical Biology, Hebei University, Baoding, Hebei 071002, China) 
Supported by the National Natural Science Foundations of China(20475015 ,20672027)
1 Results 1,3-Dipolar cycloaddition reaction is one of the most common methods for preparing various five membered heterocycles,and provides a conveniet protocols for constructing C-C bond with functional groups.The r...
关键词:1 3-Dipolar cycloaddition reaction exo-glycal NITRONE nitrile oxide 
Stereoselective Synthesis of Novel C-Disaccharides via Suzuki Cross-Coupling Reaction
《Chinese Journal of Chemistry》2005年第11期1564-1568,共5页LI, Xiao-Liu XU, Xiao-Ming TIAN, Jun LI, Ying-Xia 
Project supported by the National Natural Science Foundation of China (No. 20475015), the Natural Science Foundation of Hebei Province (No. B2005000106), the 0pen Research Fund Program of Key Laboratory of Marine Drugs (0cean University of China), and Ministry of Education of China (No. KLMD [0UC] 200407).
Novel β-C-disaccharides containing a three carbon linkage using exo-glycal as the precursor were prepared stereoselectively. The synthesis was achieved by the tandem reactions of the stereoselective hydroboration of ...
关键词:exo-glycal Suzuki coupling reaction C-DISACCHARIDE 
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