supported by grants from the Fundamental Research Funds for Central Universities(No.2042021kf0190)。
2-Deoxy-α-C-Glycosides are a significant class of carbohydrates found in numerous bioactive molecules and medicines.Developing a concise strategy for the assembly of theseα-configured C-glycosides is crucial in the ...
sponsored by the National Key R&D Program of China(Grant No.2023YFA1508800);National Science Foundation(Grant No.22301178);Shanghai Pilot Program for Basic Research-Shanghai Jiao Tong University(Grant No.21TQ1400210);Fundamental Research Funds for the Central Universities(Grant No.22X010201631);the Open Grant from the Pingyuan Laboratory(2023PY-OP-0102);Excellent Young Scientists Fund Program(Overseas),Natural Science Founda-tion of Shanghai(Grant No.21ZR1435600);Shanghai Sailing Program(Grant No 21YF1420600);start-up fundings from Shanghai Jiao Tong University(SJTU);Part of this study was supported by the National Science Foundation(Grant No.82204192 to Y.N.);National Key R&D Program of China(Grant No.2023YFC2308200 to Y.N.);Natural Science Foundation of Jiangsu Province(BK20220471 to Y.N.);Beatriu de Pinós programme from AGAUR(Grant No.2022 BP 00055 to Y.L);the China Postdoctoral Science Foundation(2022M722071 to B.Y.).
Nonclassical C-glycosides,distinguished by their unique glycosidic bond connection mode,represent a promising avenue for the development of carbohydrate-based drugs.However,the accessibility of nonclassical C-glycosid...
supported by National Natural Science Foundation of China(No.22171133);State Key Laboratory of Analytical Chemistry for Life Science(No.5431ZZXM2308)。
Glycosyl radicals,produced under mild photoredox conditions,show unique utility in the preparation of C-linked glycoconjugates.We herein report the construction of C-glycosidic bonds on α,β-dehydroalanine(DHA)of pep...
The authors are grateful for financial support provided by NSFC(22125103and21971065);STCSM(22JC1401000,20xD1421500 and 20JC1416800);the Fundamental Research FundsfortheCentral Universities.
C-aryl glycosides are an important kind of carbohydrate derivatives for drug discovery,due to their distinctive attributes of resistance to hydrolysis from enzymes.Herein,C-aryl glycosylation was established for the s...
the National Natural Science Foundation of China(21907071,21922106,and T2221004);Fok Ying Tung Education Foundation for financial support.
Comprehensive Summary,C-Glycosides are critical,naturally occurring products and medicinal candidates,and extensive efforts have been made to explore efficient approaches for creating C-glycosidic bonds.Transition-met...
Financial support from the program of the National Natural Science Foundation of China(No.21871086,Y.-Q.Z.)is gratefully acknowledged.
The highly stereoselective synthesis of diverse medicinally valuable alkynyl C-glycosides under mild and green reaction conditions remains a great challenge.Herein,we wish to report a visible-light induced photocataly...
the National Natural Science Foundation of China No.81874333;the Guangdong Foundation for Basic and Applied Basic Research No.2020A1515010926.
Anemarrhena asphodeloides is an immensely popular medicinal herb in China,which contains an abundant of mangiferin.As an important bioactive xanthone C-glycoside,mangiferin possesses a variety of pharmacological activ...
National Natural Science Foundation of China(Grant Nos.81703379 and U1801287);Key-Area Research and Development Program of Guangdong Province(Grant No.2020B1111110007);Science and Technology Planning Project of Guangdong Province(Grant No.2018B020207008);Key Laboratory Program of Guangzhou(Grant 201902010082);the Specific Research Fund for TCM Science and Technology of Guangdong Provincial Hospital of Chinese Medicine(Grant Nos.YN2016QJ05 and YN2015MS03);Key Project of High-level University Construction of Guangzhou University of Chinese Medicine(Grant No.XK2018019)。
Ten known flavonoid C-glycosides identified as 2′′-O-β-D-glucopyranosyl isovitexin(1),spinosin(2),6′′′-acetyl spinosin(3),6′′′-p-hydroxycinnamoyl-2′′O-β-D-glucopyranosyl isovitexin(4),6′′′-p-hydroxy-cin...
This work was supported by the National Natural Science Foundation of China(21672105,21725204,91753124);Natural Science Foundation of Tianjin(17JCYBJC19700,18JCZDJC32800);the Fundamental Research Funds for the Central Universities(Nankai University)(63191746).
A radical-mediated method was reported for diastereoselective synthesis of non-classical heteroaryl C-glycosides via Minisci-type alkylation of N-heteroarenes with 4-glycosyl-1,4-dihydropyridine(DHP)reagents.These DHP...
In order to systematically investigate the chemical constituents of Citri Reticulatae Folium (leaves of 'Fuju'), an analytical method that included high-performance liquid chromatography, diode array detection, el...