唾液腺显像对鼻咽癌适形调强放疗后腮腺功能的评价  

Salivary gland scintigraphy in the evaluation of parotid function after intensity-modulation radiation therapy in nasopharyngeal cancer

作　　者：黄秒[1] 肖国有[1] 李党生[1] 姚忠强[1] 邓李燕[1] 覃伟武[2] 

机构地区：[1]广西医科大学附属肿瘤医院影像学诊断中心,南宁市530021 [2]广西医科大学第一附属医院核医学科,南宁市530021

出　　处：《微创医学》2011年第5期402-404,共3页Journal of Minimally Invasive Medicine

基　　金：广西区卫生厅科研课题(合同号:Z2009241)

摘　　要：目的探讨唾液腺显像对鼻咽癌适形调强放疗(IMRT)后腮腺功能的评价。方法对30例鼻咽癌行IMRT的患者,分别于放疗前、放疗结束时及放疗后5个月作口干程度的比较及唾液腺功能显像。结果 IMRT结束时患者出现不同程度口干症状,IMRT后5个月时,部分患者口干症状有明显改善。IMRT结束时及放疗后5个月腮腺定量分析摄取指数(UI)及分泌指数(EI)均比放疗前的低(P<0.05)。结论唾液腺显像可用于观测鼻咽癌IMRT后腮腺功能变化。Objective To study the parotid function with salivary gland scintigraphy after intensitymodulation radiation therapy（IMRT） in nasopharyngeal cancer. Methods Thirty patients of nasopharyngeal cancer underwent IMRT were observed. The level of mouth dryness and the parotid function were compared among before treatment,at the end of treatment and 5 months after treatment. Results At the end of IMRT, patients were found with different degrees of mouth dryness, but improved apparently 5 months after in part of the patients. Salivary function quantitativc analysis of uptake index and excretion index at the end of IMRT and 5 moths later were lower than before IMRT（P 〈 0.05 ）. Conclusion Salivary gland scintigraphy is sensitive for monitoring parotid function after IMRT in nasopharyngeal cancer.

关 键 词：唾液腺显像 腮腺 鼻咽癌 适形调强放疗 

分 类 号：R739.63[医药卫生—肿瘤]