甘露醇治疗脑出血引起急性肾功衰竭防治的临床研究  

The Clinical research for prevention of acute renal failure caused by Mannitol treatment of cerebral hemorrhage

作　　者：曲川珍 张海军 王孝升 张玉萍 吴世新 

机构地区：[1]山东省栖霞市人民医院,210033

出　　处：《中国实用医药》2011年第20期3-4,共2页China Practical Medicine

摘　　要：目的探讨甘露醇治疗脑出血引起急性肾功衰竭的防治方案。方法对256例脑出血患者随机分为治疗组及对照组,治疗结果进行回顾性分析。结果经统计学处理肾功能衰竭的发生情况,治疗组与对照组相比差异有统计学意义(P<0.01);肾功能衰竭的转归情况,治疗组与对照组差异有统计学意义。结论甘露醇与甘油果糖联用;早期应用小剂量多巴胺、立其丁;小剂量应用甘露醇,滴速不能过快,疗程不能过长。以上方法能有效防治甘露醇治疗脑出血引起的急性肾功衰竭。Objective To explore preventive method of acute renal failure caused by mannitol treatment of cerebral hemorrhage.Methods 256 cases of cerebral hemorrhage were randomly divided into treatment group and control group.Their treatment results were retrospectively analyzed.Results There are significant differences（P〈0.01）between two groups by statistical analysis of the incidence of renal failure.And there were also exist significant differences regarding to renal failure prognosis.Conclusion Combined use of Mannitol and Glycerin Fructose;use small dose of dopamine in early stage,phentolamine,small dose of Mannitol,dripping slow and short course of treatment.The above methods can effectively prevent acute renal failure caused by Mannitol treatment of cerebral hemorrhage.

关 键 词：甘露醇 脑出血 急性肾功衰竭 甘油果糖 多巴胺 立其丁 

分 类 号：R743.34[医药卫生—神经病学与精神病学]