巨齿蛇毒发色底物法检测重症肝病患者血浆凝血酶原活性的研究  

The study on plasma factor Ⅱ coagulant activity by echis carinatus venom chromogenic substrate assay of serious hepatitis disease

作　　者：张吉林[1] 宋玉国[1] 张生昌[1] 傅平平 

机构地区：[1]吉林医学院,吉林 132001 [2]白求恩医科大学第三临床学院

出　　处：《吉林医学院学报》1999年第4期34-35,共2页

摘　　要：目的：评估血浆凝血酶原活性在重症肝病早期诊断中的应用价值。方法：采用巨齿蛇毒发色底物法检测了１００例献血员和１１５例重症肝病患者的ＦⅡ：ＣＡ，并同步检测预示重症肝病的其他指标。结果：ＦⅡ：ＣＡ正常参考范围（８５．０－１３１．０）％，重症肝病患者的ＦⅡ：ＣＡ与正常对照及预示重症肝病的其他指标比较均具有显著性差异。Objective:To evaluate application of plasma (actor Ⅱ coagulant activity (FⅡ:CA) in the early diagnosis of serious hepatitis (SH) disease.Methods:Echis carinatus venon chromogenic substrate assay (ECVCSA) was in the detection of FⅡ:CA in the plasma of 100 helth subjects and in 115 patients with SH and other terms of SH. Result:nonnal FⅡ:CA referene levels were (85.0～131.0%).FⅡ:CA of SH was more significantly higher than levels of normal group and other terms levels of SH. Conclusion:The detection of FⅡ:CA may be one of the terms of SH in the early diagnosis.

关 键 词：凝血酶原活性 重症肝病 ECVCSA 

分 类 号：R575[医药卫生—消化系统]