稀盐酸增强射频消融离体牛肝的实验研究  

Diluted Hydrochloric Acid-Enhanced Radiofrequency Ablation in Ex Vivo Bovine Livers

作　　者：许玉华[1] 黄立新[2] 许茫茫 赵异才[2] 罗荣光[2] 

机构地区：[1]江西省胸科医院内科 [2]南昌大学第一附属医院影像科介入室,南昌330006 [3]奉新县人民医院内科,江西奉新330700

出　　处：《南昌大学学报（医学版）》2011年第4期21-23,共3页Journal of Nanchang University：Medical Sciences

摘　　要：目的探讨离子型化学消融剂——稀盐酸能否增大单灌注射频电极消融范围。方法采用RITA射频消融治疗系统,按厂家推荐设定的消融时间、温度和功率分别为103℃3、0 W1、5 min,对2个完整离体牛肝进行稀盐酸增强射频消融,获得消融灶10个,测量其纵轴、横轴并计算体积。结果所有消融灶切面均为椭圆形或类椭圆形,与周围正常肝组织的分界清晰,消融灶中心呈果酱样;消融灶长轴平均为(5.51±0.06)cm,横轴平均为(4.50±0.11)cm,体积平均为(58.52±3.11)cm3。结论稀盐酸能在一定程度上增大射频消融灶范围。Objective To evaluate the influence of continuous infusion of diluted hydrochloric acid during radiofrequency ablation on the size of the ablated lesion produced.Methods According to the manufacturer＇s recommended conditions,the time,power and temperature of radiofrequency ablation were set at 103 ℃/30 W/15 minutes.Ten dilute hydrochloric acid enhanced radiofrequency ablation lesions were obtained in two entire ex vivo bovine livers.Ablation lesion volume was calculated by measuring the longitudinal and transverse diameters using the ellipsoid formula.Results All ablation lesions showed elliptical or elliptical-like shap with clear boundaries with normal hepatic tissues and the center of ablation lesions showed jam-like structures.The mean longitudinal diameters,transverse diameters and ablation volumes were（5.51±0.06）cm,（4.50±0.11）cm and（58.52 ±3.11）cm3,respectively.Conclusion To some extent,diluted hydrochloric acid can enlarge radiofrequency ablation lesions.

关 键 词：稀盐酸 射频消融 离体牛肝 

分 类 号：R-33[医药卫生]