超声-微波协同辅助盐酸水解葡萄糖制乙酰丙酸的研究  

Study on Preparation of Levulinic Acid by Hydrolysis of Glucose Using Ultrasound-Microwave Assisted Hydrochloric Acid Method

作　　者：李果[1] 李利军[1] 刘柳[1] 赖映标[1] 李伟[1] 孔红星[1] 

机构地区：[1]广西工学院生物与化学工程系,广西柳州545006

出　　处：《化学与生物工程》2011年第7期61-63,共3页Chemistry & Bioengineering

摘　　要：以葡萄糖为原料,采用超声-微波协同辅助盐酸水解法制备乙酰丙酸。应用单变量法考察了反应温度、葡萄糖与盐酸体积比、盐酸浓度、反应时间等对乙酰丙酸产率的影响,确定最佳工艺条件如下:反应温度100℃、葡萄糖与盐酸体积比1∶0.7、盐酸浓度5 mol·L-1、反应时间60 min,此时,乙酰丙酸的产率达到49.1%。该法具有反应条件温和、耗时短、产率高等特点。With glucose as raw material,the preparation of levulinic acid using ultrasound-microwave assisted hydrochloric acid method was studied.The effects of reaction temperature,volume ratio of glucose to hydrochloric acid,hydrochloric acid concentration,reaction time on the yield of levulinic acid were investigated.The optimum conditions were obtained by single variable method as follows：reaction temperature of 100 ℃,volume ratio of glucose to hydrochloric acid of 1∶0.7,hydrochloric acid concentration of 5 mol·L-1,reaction time of 60 min.Under above optimum conditions,the yield of levulinic acid reached 49.1%.The proposed method is simple and rapid with high yield compared to those reported in related literatures.

关 键 词：超声 微波 葡萄糖 乙酰丙酸 

分 类 号：TQ225.123[化学工程—有机化工] TQ91