城市地区女性和医护人员对HPV及疫苗的认知调查  

Survey on Awareness and Attitude Towards HPV and HPV Vaccination for Cervical Cancer Prevention Among Urban Women and Medical Professionals

作　　者：何美[1] 赵方辉[2] 洪颖[3] 邓继红[4] 李隆玉[5] 李联崑[6] 刘继红[7] 李倬珍[8] 刘玉玲[9] 玛依努尔.尼亚孜 杨瑛[11] 谢幸[12] 张丽琴[13] 李劼[14] 张国楠[15] 周琦[1] 乔友林[2] 

机构地区：[1]重庆市肿瘤医院,重庆400030 [2]中国医学科学院北京协和医学院肿瘤医院,北京100021 [3]南京大学医学院鼓楼医院,江苏南京210008 [4]昆明市妇幼保健院,云南昆明650031 [5]江西省妇幼保健院,江西南昌330006 [6]辽宁省肿瘤医院,辽宁沈阳110042 [7]中山大学附属肿瘤医院,广东广州510060 [8]湖北省妇幼保健院,湖北武汉430070 [9]郑州大学第二附属医院,河南郑州450014 [10]新疆自治区人民医院,新疆乌鲁木齐830001 [11]第四军医大学唐都医院,陕西西安710038 [12]浙江大学医学院附属妇产医院,浙江杭州310006 [13]天津医科大学总医院,天津300052 [14]湖南省人民医院,湖南长沙410005 [15]四川省肿瘤医院,四川成都610041

出　　处：《中国肿瘤》2011年第7期483-488,共6页China Cancer

基　　金：中国癌症基金会子宫颈癌防治专项基金

摘　　要：[目的]探讨中国城市地区女性和医护人员对HPV及疫苗的认知状况和接种意愿。[方法]采用Logisitic回归方法分析以医院为基础的机会性筛查的女性以及医护人员对HPV及疫苗的认知情况及影响接种意愿的因素。[结果]筛查女性中32.85%听说过HPV但72.31%愿意自己接种HPV疫苗,72.59%愿意让其女儿接种疫苗;而医护人员中89.62%知道HPV感染是宫颈癌的必要因素,且69.22%了解宫颈癌是可以通过疫苗预防,69.77%愿意自己接种疫苗,68.74%愿意让其女儿接种疫苗。高学历(OR=3.67～9.70)、高收入(OR=2.15～6.68)、初次性生活年龄较大(OR=1.14～1.50)、初次怀孕年龄较大(OR=1.36～1.98)、怀孕次数较少(OR=1.21～1.34)、生产次数较少(OR=1.77～2.66)的女性对HPV疫苗的接受程度较高,且均存在剂量反应关系(P<0.05);家人患有肿瘤(OR=1.41,95%CI:1.20～1.65)、听说过HPV(OR=2.68,95%CI:2.33～3.07)者更愿意接种疫苗。不愿意接种疫苗的主要原因是认为HPV疫苗还没有大面积推广(筛查女性占43.55%,医护人员占39.84%)且不认为自己有这方面的危险(筛查女性占26.21%,医护人员占38.28%);而对于疫苗的付费途径,希望国家负担全部费用的筛查女性占41.46%,医护人员占35.76%,希望国家负担部分费用的筛查女性占14.33%,医护人员占43.31%。[结论]筛查女性对HPV及疫苗认知低,但大多数女性均愿意接种疫苗,而高学历、高收入、家族有肿瘤史、听说过HPV者更愿意接种疫苗。因此,关于HPV及疫苗知识的宣传教育,应根据不同的社会文化背景来制定,尤其是针对医护人员,需要更多有关疫苗安全性和有效性的证据来提高接种意愿,达到疫苗防治宫颈癌的目的。[Purpose] To investigate Chinese urban women＇s and medical professionals＇ perception of human papillomavirus（HPV） vaccination and their intention to be vaccinated.[Methods] The survey on awareness and attitude towards HPV and vaccination were conducted among women undergoing opportunistic screening and among medical professionals in the hospital.The data were analyzed with the multivariable unconditional logistic regression.[Results] Despite awareness of HPV（32.85%） were low,willingness to be vaccinated against HPV（72.31%） was relatively high in urban women,especially willingness to their daughter（72.59%）.About 89.62% of the medical professionals knew that the HPV infection was necessary factor for cervical cancer and 69.22% knew vaccination against cervical cancer,most（69.77%） of them indicated that they would like to be vaccinated as well as to their daughter（68.74%）.Those who had higher education（adjusted odds ratio,3.67 to 9.70） or higher income （adjusted odds ratio,2.15 to 6.68） or initial sexual activity in elder age （adjusted odds ratio,1.14 to 1.50） or first pregnancy in old age （adjusted odds ratio,1.36 to 1.98）,fewer pregancies（adjusted odds ratio,1.21 to 1.34）,and fewer births （adjusted odds ratio,1.77 to 2.66） were related to higher willingness of HPV vaccination with the dose response relationship（P0.05）.Women who had family member with cancer （adjusted odds ratio,1.41 and 95% CI：1.20 to 1.65）,or who were informed about HPV infection （adjusted odds ratio,2.68 and 95% CI：2.33 to 3.07） more likely accepted vaccination than those who did not.HPV vaccination not being widely accepted and not considering themselves at risk of cervical cancer were major reasons for unwillingness of vaccination,with 43.55%,26.21% of urban women and 39.84%,38.28% of medical professionals,respectively.There was 41.46% and 14.33% of urban women,35.76% and 43.31% of medical professional thought that the government should be responsibility to pay all for the vac

关 键 词：宫颈癌 HPV疫苗 认知 意愿 

分 类 号：R730.1[医药卫生—肿瘤]