非透析肾脏病患者心理抑郁状态及其影响因素的探讨  

Depression status and its related factors in non-dialysis patients with renal disease

作　　者：张慧玲[1] 王力宁[1] 范秋灵[1] 樊怡[1] 王娟[1] 孙达[1] 姚丽[1] 栗霄立[1] 

机构地区：[1]中国医科大学附属第一医院肾内科,沈阳110001

出　　处：《临床肾脏病杂志》2011年第7期321-323,共3页Journal Of Clinical Nephrology

摘　　要：目的分析非透析肾脏病患者抑郁状态及其影响因素。方法采用描述性设计，对759例非透析肾脏病患者应用汉密顿抑郁量表（HAMD）进行评分，得分〉17分为抑郁状态（抑郁组）269例；≤17分为非抑郁状态（非抑郁组）490例。比较2组的基本情况、实验室检查以及应用激素方面是否具有统计学差异。结果非抑郁组35．44％患者有不同程度的抑郁，明显高于普通人群。2组患者在家庭收入等方面无统计学差异，而年龄、血型（A型）、碳酸氢根和补体C3具有统计学意义（P〈0．05）。结论非透析肾脏病患者抑郁发生率高于普通人群；家庭收入与抑郁之间无统计学差异；低碳酸氢根、补体C3、血型（A型）是抑郁的危险因素，年龄是其保护因素。Objective To explore the depression status and its influencing factors in nephrology patients without dialysis. Methods A descriptive design was used to conduct this study. 759 patients without dialysis were assessed by Hamilton Depression Scale （HAMD）. In terms of the score of HAMD, patients were divided into two groups： depression group （score〉 17） ; non-depression group （score≤17）. The basic situation, the relevant laboratory tests and use of steroids in two groups were analyzed. Results 35.44% of patients had different degrees of depression,which was higher than the general population. There are not important differences in income between two groups. There was sig- nificant difference in age, blood type （A）, bicarbonate and complement C3 between two groups （P〈 0. 05）. Conclusion The depression incidence in non-dialysis patients with kidney disease is significantly higher than the general population. There is no significant correlation between income and depression occurrence. Low bicarbonate, low complement C3 and A-type blood are risk factors for nondialysis patients with depression,but the age is protective factor for depression.

关 键 词：肾病 抑郁 影响因素 

分 类 号：R57[医药卫生—消化系统]