SYNTHESIS AND PHASE BEHAVIOR OF POLYURETHANES END-CAPPED WITH FLUORINATED PHOSPHATIDYLCHOLINE HEAD GROUPS  

作　　者：谭鸿 傅强 

机构地区：[1]College of Polymer Science and Engineering,State Key Laboratory of Polymer Materials Engineering, Sichuan University

出　　处：《Chinese Journal of Polymer Science》2011年第5期615-626,共12页高分子科学（英文版）

基　　金：financially supported by the National Natural Science Foundation of China(No.50673063);Program for the New-Century Excellent Talents of Ministry of Education of China(NCET-08-0381);Sichuan Provincial Science Fund for Distinguished Young Scholars(09ZQ026-024)

摘　　要：A series of fluorinated phosphatidylcholine polyurethane macromolecular additives were synthesized by solution polymerization using methylenebis（phylene isocyanates） （MDI） and 1,4-butanediol （BDO） as hard segments, a new phoshporycholine, 2-（2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9-hexadecafluoro-10-（2-hydroxyethoxy）decyloxy） ethyl phosphorycholine （HDFOPC） as end-capper, and four polydiols, poly（tetramethylene glycol）s （PTMG）, polydimethylsiloxane （PDMS）, poly（1,6-hexyl-1,5-pentylcarbonate） （PHPC） and poly（propylene glycol） （PPG） as soft segments, respectively. The chemical structures of the synthesized polyurethanes were characterized by 1H-NMR and FTIR. DSC and DMA were employed to study the phase behavior of these novel polyurethanes due to their great influences on the surface properties, and hence their interactions with bio-systems. The results showed that phase separation of the fluorinated phosphatidylcholine end-capped polyurethanes was increased in comparison with that of normal polyurethanes. The effect of fluorinated phosphatidylcholine end-capped groups on the phase behavior was further demonstrated by analyzing the degree of hydrogen-bonding between hard and soft segments.A series of fluorinated phosphatidylcholine polyurethane macromolecular additives were synthesized by solution polymerization using methylenebis（phylene isocyanates） （MDI） and 1,4-butanediol （BDO） as hard segments, a new phoshporycholine, 2-（2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9-hexadecafluoro-10-（2-hydroxyethoxy）decyloxy） ethyl phosphorycholine （HDFOPC） as end-capper, and four polydiols, poly（tetramethylene glycol）s （PTMG）, polydimethylsiloxane （PDMS）, poly（1,6-hexyl-1,5-pentylcarbonate） （PHPC） and poly（propylene glycol） （PPG） as soft segments, respectively. The chemical structures of the synthesized polyurethanes were characterized by 1H-NMR and FTIR. DSC and DMA were employed to study the phase behavior of these novel polyurethanes due to their great influences on the surface properties, and hence their interactions with bio-systems. The results showed that phase separation of the fluorinated phosphatidylcholine end-capped polyurethanes was increased in comparison with that of normal polyurethanes. The effect of fluorinated phosphatidylcholine end-capped groups on the phase behavior was further demonstrated by analyzing the degree of hydrogen-bonding between hard and soft segments.

关 键 词：Polyurethanes PHOSPHORYLCHOLINE SYNTHESIS Phase behavior. 

分 类 号：O631.5[理学—高分子化学]