p16在食管癌变过程中的表达  

Expression of p16 in Carcinogenesis of the Esophagus

作　　者：刘海明[1] 

机构地区：[1]河南护理职业学院附属医院,安阳455000

出　　处：《中国医疗前沿》2011年第12期14-15,共2页China Healthcare Innovation

摘　　要：目的探讨p16基因在食管癌变过程中的表达。方法应用免疫组织化学S-P法检测p16基因在17例癌变组和40例非癌变组中的表达。结果 p16在癌变组中的表达降低(P<0.05)。结论 p16基因的表达和食管癌的发生有关,p16基因表达的变化可能是食管癌发生中的早期事件。Objective To study the expression of p16 gene in esophageal carcinogenesis.Methods Immunohistochemical S-P method was used to detect the expression of p16 gene in 17 cases of canceration group,40 cases of non-canceration group.Results The expression of p16 was lower in canceration group（P0.05）.Conclusions The expression of p16 was related to esophageal carcinogenesis,and its change maybe was early event in esophageal carcinogenesis.

关 键 词：P16 食管癌变过程 免疫组织化学 

分 类 号：R365[医药卫生—病理学]