人参皂苷的体外模拟代谢及转化研究进展  

Advances in studies on metabolism and biotansformation of ginsenosides in vitro

作　　者：范利荣[1] 史海明[1] 李晓波[1] 

机构地区：[1]上海交通大学药学院,上海200240

出　　处：《中国中药杂志》2011年第15期2021-2026,共6页China Journal of Chinese Materia Medica

基　　金：国家自然科学基金项目(30973962)

摘　　要：人参系传统名贵中药,近年来对其代谢的研究成为热点。通过查阅国内外相关文献,作者主要从人工胃液、肠道菌代谢、酶和微生物体外转化4个方面对人参皂苷体外模拟代谢及转化进行阐述,分析人参皂苷体外代谢的主要途径,为人参皂苷代谢的系统性研究提供参考。As a famous traditional Chinese medicine, ginseng＇s metabolism has been a hot spot in recent years. In this review, relevant literatures on the research progress of the metabolism of ginsenosides in vitro have been introduced. This review focuses on ar- tifieal juice metabolism, intestinal bacteria metabolism, microbial and enzymatic biotransformation of ginsenosides. Main metabolic pathways of ginsenosides in vitro are also analyzed, which will provide a reference for the systematic study on metabolism of ginsen- osides.

关 键 词：人参皂苷 体外模拟代谢 人工胃液 肠道菌代谢 微生物转化 酶转化 

分 类 号：R285[医药卫生—中药学]