烫狗脊炮制过程的化学反应及产物研究  

Chemical reaction and products in processed Cibotium barometz

作　　者：许枬[1] 贾天柱[1] 

机构地区：[1]辽宁中医药大学,辽宁大连116600

出　　处：《中国中药杂志》2011年第15期2066-2070,共5页China Journal of Chinese Materia Medica

基　　金：国家自然科学基金项目(30572371;30825047)

摘　　要：目的:研究狗脊炮制过程中化学成分的变化和机制。方法:采用薄层色谱法、高效液相色谱法研究狗脊炮制前后化学成分变化,并利用色谱法分离鉴定了炮制前后有明显变化的化学成分。结果:狗脊炮制前后化学成分有较大变化。结论:狗脊炮制过程中发生了梅拉德反应,所引起的化学成分变化可能是狗脊炮制前后功效变化的主要原因。Objective： To investigate the chemical variation and its mechanism in processing of Cibotium barometz. Method： The methods of TLC and HPLC were carried out to identify the chemical variation in processing of C. barometz, and the compounds changed significantly were isolated by chromatography. Result： Chemical components were changed significantly in processing of C. barometz. Conclusion： Maillard reaction is involved in the process of rhizome C. barometz, which may be contributed to the activity between raw and processed C. barometz.

关 键 词：狗脊 炮制 化学成分变化研究 梅拉德反应 

分 类 号：R284[医药卫生—中药学]