复发性脑梗死与血清超敏C反应蛋白关系探讨  

Relationship between recurrence of cerebral infarction and the level of high sensitivity C-reactive protein

作　　者：潘燕[1] 张保朝[1] 

机构地区：[1]河南南阳市中心医院神经内科,南阳473000

出　　处：《中国实用神经疾病杂志》2011年第13期25-27,共3页Chinese Journal of Practical Nervous Diseases

摘　　要：目的观察脑梗死初发、复发患者血清CRP水平,探讨脑梗死复发与血清CRP的关系。方法用免疫透射比浊法测定200例急性脑梗死患者及100例非急性脑卒中患者的血清CRP水平,并进行分析。结果各类型急性脑梗死患者血清CRP均高于非急性脑卒中患者(P<0.01);各类型脑梗死患者之间血清CRP差异无统计学意义(P>0.05)。脑梗死复发患者血清CRP高于初发患者(P<0.01),且高血清CRP比率亦高于初发患者(P<0.05)。各类型脑梗死复发患者之间血清CRP差异无统计学意义(P>0.05)。结论脑梗死复发患者血清CRP高于初发患者提示脑梗死复发与血清CRP升高有一定关系,高血清CRP是脑梗死复发的独立性危险因素。Objective To study the relationship between the high sensitivity C-reactive protein and recurrent cerebral infarction（RCI）.Methods The levels of high sensitivity C-reactive protein in 200 patients with acute cerebral infarction（ACI） and 100 non-ACI patients（as controls） were detected by enhanced immunoturbidimetic assay,and were analyzed.Results Plasma levels of hs-CRP in all these patients were significantly higher than those in the controls（P0.01） and there were no significant differences between the levels in patients with various types of infarction（P0.05）.Plasma hs-CRP levels in patients with recurrent infarction were significantly higher than those in patients with infarction for the first time（P0.01）,the percentage of the subjects in the recurrent group with higher hs-CRP plasma level was also higher than that in group with first time infarction（P0.05）.Among the recurrent patients,plasma hs-CRP levels in patients with thrombosis were slightly higher than those in patients with recurrence due to other causes but not significant（P0.05）.Conclusion hs-CRP may be an independent risk factor associated with RCI.

关 键 词：脑梗死 复发 超敏C反应蛋白 危险因素 

分 类 号：R743.33[医药卫生—神经病学与精神病学]