疣状胃炎的胃镜及病理结果分析  

Endoscopic and pathological features of verrucous gastritis

作　　者：卜煜锋[1] 张晓海[1] 桑旭东[1] 高丽琴[1] 褚利娟[1] 施惠娟[1] 

机构地区：[1]浙江省皮肤病防治研究所(浙江武康疗养院),浙江德清武康313200

出　　处：《中国内镜杂志》2011年第7期692-694,698,共4页China Journal of Endoscopy

摘　　要：目的探讨疣状胃炎的胃镜及病理特点。方法对94例经胃镜检查符合疣状胃炎诊断标准的患者在最大疣状隆起处及距该隆起病变边缘5cm的平坦胃黏膜处各取胃黏膜组织2块,并根据其胃镜表现进行分型和其病理结果进行分析。结果疣状隆起部位黏膜萎缩及不典型增生共有59例(62.77%),而疣状病灶旁5cm平坦部位黏膜萎缩及不典型增生仅有20例(21.28%),两者之间差异有显著性(P<0.01);94例疣状胃炎患者中未成熟型46例,成熟型48例,成熟型组患者病变部位黏膜萎缩及不典型增生较非成熟型组有增加趋势,但两组之间差异无显著性(P>0.05);94例疣状胃炎患者中伴幽门螺杆菌感染者有35例,阳性率为37.23%。结论疣状隆起病灶部位更易于向萎缩性胃炎转化,提示可能是胃癌的癌前期疾病。[Objective] To investigative the endoscopic and pathological features of verrucous gastritis.[Methods] All 94 cases patients in accordance with the endoscopic diagnostic criteria of verrucous gastritis were classified,two pieces of gastric mucosal specimens from the mucosal protrusion and the flat gastric mucosa 5 cm from the edge of elevated lesion were obtained,pathological findings were analyzed.[Results] 59 cases with verrucous lesion showed mucosal atrophy and dysplasia（62.77%）,and 20 cases with mucosal lesion of flat of 5 cm from the edge of elevated lesion showed mucosal atrophy and dysplasia,（21.28%）,the difference between the two groups was significant（P 0.01）.in 94 cases of verrucous gastritis,there were 46 cases in the immature,48 cases in the mature,mucosal lesions of atrophy and dysplasia in the mature showed tendency to grow in number,but no significance between the two groups（P 0.05）.Of 94 cases of verrucous gastritis,35 cases showed Helicobacter pylori infection,the positive rate was 37.23%.[Conclusions] The focuses of mucosal protrusion are easier to transformation to atrophic gastritis,it suggests verrucous gastritis may be a kind of precancerous disease.

关 键 词：疣状胃炎 胃镜检查 病理 螺杆菌感染 

分 类 号：R573[医药卫生—消化系统] R574[医药卫生—内科学]