血管搭桥手术与内科治疗烟雾病的预后分析  

Analysis on the prognosis of vascular anastomosis therapy and medical treatment on moyamoya disease

作　　者：李经纶[1] 宋来君[1] 王本瀚 张长远 

机构地区：[1]郑州大学第一附属医院神经外科,450052 [2]解放军153中心医院神经外科

出　　处：《中国实用医刊》2011年第16期6-8,共3页Chinese Journal of Practical Medicine

摘　　要：目的对烟雾病（MMD）患者采用不同的治疗方法（内科治疗和手术治疗），比较两者差异。方法选择2005年11月至2008年8月收入住院治疗的烟雾病患者35例，将其分为两组：内科治疗组（21例），手术治疗组（14例）。对全部患者的临床资料及随访结果进行分析对照研究。结果两组患者再出血率及再发缺血症状比较差异无统计学意义（P〉0．05），两组患者自第一次发病后至今的恢复情况差异均无统计学意义（P〉0．05）。，结论手术治疗在治疗缺血型MMD上已确立了其肯定的地位，但如何预防MMD的缺血性和出血性卒中还有待于大宗病例的随机研究；手术治疗对于烟雾病患者远期症状恢复并未发现肯定的疗效。Objective Using different therapeutic method （expectant treatment and operative treatment） with moyamoya disease（MMD） patients, we can study the difference of therapeutic effect between expectant treatment and operative treatment. Methods Total 35 moyamoya disease patients in our hospital from November 2005 to August 2008. They were divided into two groups： in operative treatment group there were 14 patients, who received surgery therapy;in medical treatment group there were 21 pa- tients, who only received medical treatment. The clinical datas of all patients and follow - up results were analyzed. Results Both groups in the rebleeding rate and recurrence of ischemic symptoms had no sta- tistical significance （ P 〉 0. 05 ） , since the first two groups were compared after the onset of recovery since, there was no significant difference （P 〉 0.05）. Conclusions Surgery in the treatment of ischemic MMD has been definitely established its position, but how to prevent the MMD of isehemic and hem- orrhagic stroke cases have yet to be large randomized study. Surgical treatment of symptoms for patients with longterm restoration did not find a positive effect.

关 键 词：烟雾病 血管搭桥手术 内科治疗 

分 类 号：R743.3[医药卫生—神经病学与精神病学]