组胺、组胺受体拮抗剂与精神分裂证  

Histamine,histamine receptor antagonists and schizophrenia

作　　者：胡冰霜[1] 杨若一 Hu Bingshuang, Yang Ruoyi （1 Research Institute of Psychology, School of Public Administration, Sichuan University, Chengdu, 610064 2 Sichuan Tianlu Research Center for Nature and Ecology, Chengdu, 610041 ）

机构地区：[1]四川大学公共管理学院心理学研究所 [2]四川天麓自然生态研究中心,四川成都610041

出　　处：《科海故事博览：科技探索》2011年第7期4-6,共3页

摘　　要：组胺可以诱导过敏；而组胺受体拮抗荆可以对抗过敏；组胺和组胺受体拮抗刺都是活跃的神经递质。春天是过敏“花粉热”的季节，也是精神分裂症的发作季节；因此，关于精神分裂症的病因曾有过经典的“大脑过敏”学说。某些组胺受体拮抗荆有抗过敏与抗精神病的交叉活性。很多典型的和非典型的抗精神病药也有组胺受体拮抗作用与抗过敏的作用。本文综述了组胺、组胺受体拮抗剂与精神分裂症的关系，以及免疫问题和其他相关问题。Histamine inducesallergy; histamines receptor antagonists reduce allergy, both also areactive neurotransmitters.Spring is allergic ＂hay fever＂ season, also the season when schizophrenia attacks more; therefore, for the cause of schizophrenia there was a classictheoryof ＂cerebral allergy＂. Some of the histamine receptor antagonistshave the cross activities of anti-allergy and anti-psychotics; many typical and untypical antipsychotics also have histamine receptors antagonists effects as well as anti-allergic effects. Relationship amonghistamine ,antihistamine and schizophrenia, immunologyas well as someother related issues are reviewed.

关 键 词：组胺 组胺受体拮抗剂 精神分裂症 过敏 免疫 

分 类 号：R749.3[医药卫生—神经病学与精神病学;医药卫生—临床医学]