奈达铂放化疗同步增敏作用于头颈部鳞癌的体会  

Experience of chemoradiotherapy head and Neck squamous cancer with Nedaplantin

作　　者：张新忠[1] 陈晓芳[1] 程媛[1] 杨少华[1] 邓淼盛[1] 丁小凡[1] 

机构地区：[1]南方医科大学附属深圳宝安医院放疗科,深圳518101

出　　处：《医药论坛杂志》2011年第12期27-29,共3页Journal of Medical Forum

摘　　要：目的探讨奈达铂(NDP)放化疗同步增敏作用、毒性反应,以及处理措施。方法 NDP化疗为主方案(NDP+5Fu)的应用和放射治疗(RT)的同步进行。结果近期疗效CR57例,PR18例,骨髓抑制:WBC多为Ⅰ°,61例,约占81.3%,PletⅠ°,25例,约占33.3%,HbⅠ°,18例,约占24.0%。胃肠道反应轻。结论增敏作用肯定,耐受好。WBC影响相对小,而Plet、Hb影响略高,胃肠反应较小,无需水化。Objective To explore nedaplatin（NDP） effect,toxin reaction and treatment method.Methods Treatment with NDP＋5Fu and radiotherapy（RT） add chemotherapy together.Results Bone marrow： WBCⅠ°,61cases,about 81.3%,PletⅠ°,25cases,about 33.3%,HbⅠ°,18cases,about 24.0%,the reactions of gastrointernational tract is small.Conclusions Radiosensitizing effect is sure,endurance is fine.It has a little relatively influence upon WBC,has a little high influence upon plet、Hb.And the reaction of gastrointernational tract is a light,it is no necessary to hydrate.

关 键 词：奈达铂 放疗增敏 放化疗 头颈部鳞癌 

分 类 号：R739.91[医药卫生—肿瘤]