糖皮质激素治疗重症急性胰腺炎的效果  

THE EFFECT OF ADRENOCORTICAL HORMONE IN THE TREATMENT OF SEVERE ACUTE PANCREATITIS

作　　者：陈崇宏[1] 赵宗刚[1] 程建渊[1] 徐兆训[1] 陈咸增[1] 

机构地区：[1]青岛医学院第二附属医院普外科,青岛266042

出　　处：《青岛医学院学报》1999年第4期270-271,共2页Acta Academiae Medicinae Qingdao Universitatis

摘　　要：①目的　观察糖皮质激素（激素）治疗重症急性胰腺炎（ＳＡＰ）效果。②方法　对１９９５ 年３ 月～１９９７年１０ 月收治的２６ 例应用激素治疗的ＳＡＰ病人（观察组）进行回顾性分析，并与１９９２ 年１ 月～１９９５ 年３ 月收治的３１例未用激素治疗的病人进行对照。③结果　观察组急性反应期多器官功能衰竭发生率，感染期腹腔、胰周脓肿等并发症明显少于对照组（ｔ＝ ４．１１３～１２．９８０，Ｐ＜ ０．０５，０．０１），而且病死率也由２９％ 降至８％ （χ２＝ ４．１３４，Ｐ＜ ０．０５）。④结论　及早、足量加用糖皮质激素治疗ＳＡＰ有更好的效果。Objective\ To investigate the effect of adrenocortical hormone (ACH) in severe acute pancreatitis (SAP). Methods\ The records of 57 inpatients with SAP (from January 1992 to October 1997) were retrospectively analysed, Of which, 26 cases were treated with ACH and 31 cases treated without ACH (control group).\ Results\ In the ACH group, the MOF incident rate in the acute period was lower and the complications of abdominal and pancreatic abscesses in the infection period were obviously fewer than those in the control group ( t=4.113-12.980, P <0.05,0.01), the mortality rate decreased from 29% to 8% ( χ 2=4.134,P <0.05).\ Conclusion\ In the early period of SAP, the use of ACH can decrease the complication and the mortality rate.\;

关 键 词：胰腺炎 激素疗法 SAP 糖皮质激素 

分 类 号：R576.05[医药卫生—消化系统] R977.11[医药卫生—内科学]