多弹头射频与介入联合治疗肝癌的综合疗效观察  

The Observation of Comprehensive Efficacy of Combined With the Involvement of Multi-bullet Radiofrequency Treatment of Liver Cancer

作　　者：余智渊[1] 

机构地区：[1]湖南省肿瘤医院内科,湖南长沙410013

出　　处：《中国医药指南》2011年第22期207-208,共2页Guide of China Medicine

摘　　要：目的观察多弹头射频技术与介入技术联合用于中晚期肝癌患者的治疗综合疗效。方法选取240例原发性中晚期肝癌患者作为研究对象,将所有患者随机分为对照组和观察组,对照组患者采用选择性肝动脉化疗栓塞治疗,观察组患者在对照组治疗的基础上联合多弹头射频技术治疗。比较两组患者手术前后的临床症状改善情况、AFP浓度变化、CT影响检查变化及术后不良反应情况。术后随访1年,比较两组患者的1年生存率。结果两组患者术后临床症状改善、AFP下降、CT影像检查肿瘤缩小及随访1年的1年生存率相比较,观察组患者均具有明显的优势,P值均<0.05,有统计学意义;两组患者在介入治疗术后大部分都出现恶心、呕吐、疼痛等现象,观察组患者在多弹头射频治疗后大多出现发热、肝区疼痛等现象。经对症治疗后均得到缓解并消失。结论多弹头射频技术联合介入治疗技术治疗中晚期肝癌患者具有创伤小、操作简单、疗效确切的优势,且两种方法优势互补,彼此强化了对肝癌细胞的杀灭效率。Objective To observe the comprehensive efficacy of combined with the involvement of multi-bullet radiofrequency treatment of liver cancer.Methods 240 cases of patients with advanced liver cancer as a primary object of study,and all patients were randomly divided into control group and observation group.Control group were treated with selective hepatic artery chemoembolization,and observation group joint multi-bullet radiofrequency technology on the treatment based on the control group.Compared clinical symptoms,AFP concentration,CT affect change and postoperative examination of toxicity for two groups of patients before and after the improvement.Patients were followed up one year,and compared 1-year survival.Results Postoperative clinical improvement,AFP decline,CT imaging and tumor shrinkage followed up for 1-year 1-year survival compared to observation patients have obvious advantages,P 0.05,and there was statistically significant.Most of the two groups patients had phenomena of nausea,vomiting,pain and others after interventional treatment.Most of the observation group appeared multi-bullet radiofrequency fever,liver pain and other phenomena.After symptomatic treatment,the phenomena were eased and disappeared.Conclusion Multi-bullet radiofrequency technology combined interventional therapy have trauma,simple,and effective advantage in the treatment of patients with advanced liver cancer.And two methods complement each other to strengthen the effectiveness of killing cancer cells.

关 键 词：中晚期肝癌 多弹头射频技术 选择性肝动脉化疗栓塞 

分 类 号：R735.7[医药卫生—肿瘤]