^(18)F-FDG PET/CT与MRI对乳腺癌诊断价值的比较  

Comparison of diagnosis value between ^(18)F-FDG PET/CT and MRI in breast cancer

作　　者：赵继红[1] 丁军[2] 徐松柏[3] 王显荣[2] 付卫光[2] 

机构地区：[1]吉林省肿瘤医院放射线科,吉林长春130012 [2]吉林大学中日联谊医院放射线科,吉林长春130033 [3]吉林大学第一医院神经外科,吉林长春130021

出　　处：《吉林大学学报（医学版）》2011年第4期746-749,共4页Journal of Jilin University：Medicine Edition

基　　金：吉林省科技厅科技发展计划项目资助课题(200905170)

摘　　要：目的:比较18F-FDG PET/CT和MRI在乳腺癌诊断中的作用。方法:选择29例怀疑乳腺癌的患者作为研究对象,10d内进行PET/CT、MRI检查及得到病理结果。以病理结果作为金标准,计算18 F-FDG PET/CT和MRI诊断乳腺癌的灵敏度、特异度及准确度。结果:组织病理学证实在29例患者中,良性肿瘤9例,恶性肿瘤20例。MRI评价乳腺癌的灵敏度、特异度、准确率分别为85.0%、66.7%和79.3%,PET/CT灵敏度、特异度、准确率分别为90.0%、88.9%和89.6%,PET/CT诊断准确度要高于乳腺MRI,但两者之间差异无统计学意义(χ2=1.17,P>0.05);PET/CT通过全身显像还显示了未预测到的左侧锁骨上淋巴结及骨转移3例。结论:在乳腺癌原发灶诊断准确性方面,PET/CT与MRI差异无统计学意义,但在揭示远处转移、准确分期以指导临床治疗方面,PET/CT要优于乳腺MRI。Objective To compare the effects between 18F-fluorodeoxyglucose（18F-FDG）PET-CT and MRI in diagnosis of breast cancer.Methods 29 patients with suspicious masses in breast were selected,^18F-FDG PET/CT and MRI scanning were performed and their pathological results were gotten within 10 d.The sensitivities,specificities and accuracies of PET/CT and MRI in detecting breast cancer were calculated by using surgery or biopsy results as diagnostic golden standard.Results 20 malignant and 9 benign breast lesions of the 29 patients were proven histologically after surgery or biopsy.The sensitivity,specificity and accuracy value obtained by MRI were 85.0%,66.7% and 79.3% respectively,and they were 90.0%,88.9% and 89.6% for PET/CT.The accuracy of PET/CT was a little higher than that of MRI,but there was no significant difference between them（χ^2=1.17,P〉0.05）.PET/CT found 3 patients with left infraclavicular lymph node metastasis and bone metastasis.Conclusion There is no significant difference between PET/CT and MRI in detecting breast cancer.But PET/CT is superior to MRI in evaluating distant metastasis and accurate staging to guide therapy.

关 键 词：乳腺肿瘤 正电子发射型计算机断层显像 核磁共振成像 

分 类 号：R737.9[医药卫生—肿瘤]