驻南方某部军人反流性食管炎及幽门螺杆菌感染情况分析  

The prevalence of reflux esophagitis and Helicobacter pylori infection in troops stationed in southern China

作　　者：王雯[1] 庄惠军[1] 沈许德[1] 王蓉[1] 李达周[1] 张志坚[1] 

机构地区：[1]南京军区福州总医院消化内科,福州350025

出　　处：《解放军医学杂志》2011年第8期860-862,共3页Medical Journal of Chinese People's Liberation Army

基　　金：南京军区医药卫生科研重点项目(07Z035)

摘　　要：目的研究南方某部军人反流性食管炎（RE）的患病情况及其与幽门螺杆菌（Hp）感染的关系。方法选择通过反流性疾病问卷（RDQ）调查诊断为胃食管反流病（GERD）的91例军人病例作为GERD组,并根据症状积分分为低分组（12~15分）47例,中分组（16~20分）34例,高分组（〉20分）10例。另随机抽取60例非GERD军人（反流症状评分〈12分）为对照组。共151例军人接受胃镜检查,同时采用14C-尿素呼气试验（14C-UBT）和快速尿素酶试验（RUT）两种方法检测Hp,结果均阳性者判为Hp感染。结果 GERD组与对照组的RE检出率分别为42.9%（39/91）和3.3%（2/60）,两组比较差异有统计学意义（P〈0.05）,但GERD各积分组之间的RE检出率差异无统计学意义（P〉0.05）。GERD组中检出39例RE,其中A、B级分别为221、3例（共占89.7%）,C、D级分别为31、例（共占10.3%）;另检出8例Barrett食管（BE,8.8%）。RE症状积分与分级之间无明显线性关系（r=0.276,P〉0.05）。RE患者Hp感染率为59.0%（23/39）,与对照组（61.7%）比较差异无统计学意义（P〉0.05）。结论军人RE检出率及Hp感染率均较高,RE检出率与Hp感染无明显关联。Objective To assess the prevalence of reflux esophagitis（RE） in troops stationed in southern China,and explore the relationship between RE incidence and Helicobacter pylori（Hp） infection.Methods Ninety-one confirmed gastroesophageal reflux disease（GERD） patients were selected,with lower score in 47,（Sc： 12-15）,moderate score（Sc： 16-20） in 34,and high score（Sc 20） in 10.Sixty non-GERD servicemen with Sc12 served as control group by stratified random sampling method.All the 151 subjects underwent gastroscopy.Hp infection was detected by 14C urea breath test（14C-UBT） and rapid urease test（RUT）.Hp infection was confirmed by the positive results of the both tests.Results The diagnostic rate of RE was significantly higher in GERD group（42.9%,39/91） than in control group（3.3%,2/60,P0.05）.No statistical difference in RE was found among those in different GERD scores（P0.05）.In GERD group,thirty-nine RE patients were found with 22 cases in grade A,13 in grade B,3 in grade C and 1 in grade D.Of the 39 RE patients,35（89.7%） were in low grade（grade A and B）.Eight patients（8.8%） in GERD group were found to suffered from Barrett＇s syndrome.No significant correlation was shown between the degree of RE and GERD scores（r=0.276,P0.05）.There were no significant difference in infection rate of Hp between the RE patients（59.0%,23/39） and those in control group（61.7%,37/60,P0.05）.Conclusions The prevalence of RE is high in troops stationed in southern China.No correlation is found between the rate of RE and Hp infection.

关 键 词：食管炎 消化性 螺杆菌 幽门 患病率 胃镜检查 军事人员 

分 类 号：R571.9[医药卫生—消化系统]