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作 者:李媚[1] 刘杏[1] 钟毅敏[1] 曹丹[1] 杨晔[1] 曾阳发[1]
机构地区:[1]中山大学中山眼科中心眼科学国家重点实验室,广东广州510060
出 处:《中国实用眼科杂志》2011年第8期789-793,共5页Chinese Journal of Practical Ophthalmology
基 金:广东省科技计划项目(20088030301334)广东省医学科研课题(B2009085)
摘 要:目的观察原发性急性闭角型青光眼(acute primary angle closure glaucoma, APACG)周边虹膜切除(peripheral iridectomy,PI)和小梁切除术(Trabeculectomy,Trab)手术前后眼前段结构参数的改变。方法临床病例对照研究。对2009年6—12月在中山大学眼科中心连续性收集57例57只眼APACG患者,周边虹膜粘连(peripheral anterior synechiae,PAS)范围≤6个钟点者行PI术,PAS范围〉6个钟点者行小梁切除术,术前及术后3月行眼前段光学相干断层扫描仪(anterior segment optical coherence tomography, AS-OCT)眼前段扫描。比较两组组内及组间术前及术后的中央前房深度(central anterior chamber depth,ACD)、房角开放距离(angle opening distance,AOD)、小梁网虹膜间面积(Trabecular iris area,TISA)、房角隐窝面积(angle recess area,ARA)、前房宽度(anterior chamber width,Acw)、前房容积(anterior chamber volume,Acv)和晶状体矢高(crystalline lens rise, CLR)。结果两组间的平均年龄(t=-0.176,P=0.862)和性别(P=0.390)之间无统计学差异。术前及术后周边虹膜切除术组的TISA和ARA均明显大于小梁切除术组(P=0.013~0.049o周边虹膜切除术组术后AOD、TISA、ARA及ACV较术前明显增加(P〈0.001~0.044),ACD、ACW及CLR手术前后无明显变化(P=0.102-0.609)。小梁切除术组术后除ACV较术前的增加有统计学意义外(P〈0.001),余参数手术前后无变化(P=0.056~0.585)。结论周边虹膜切除术和小梁切除术均可增加APACG眼的ACV,但ACD和CLR无明显改变。周边虹膜切除术术后APACG眼房角参数改善,但小梁切除术对房角参数的改变无明显影响。Objective To evaluate the changes in anterior segment configuration after peripheral iridectomy (PI) or trabeculectomy (Trab) in acute primary angle closure glaucoma (APACG). Methods Fifty-seven eyes of 57 patients with APACG were successive collected. PI was performed to those patients with the clock hours of peripheral anterior synechiae (PAS) 6, while Trab was performed to those patients with the clock hours of PAS 〉6. Anterior segment optical coherence tomography (AS-OCT) examination was performed before and 3 months after PI/Trab to compare Central anterior chamber depth (ACD), angle opening distance (AOD), trabecular iris area (TISA), angle recess area (ARA), anterior chamber width (ACW), anterior chamber volume (ACV) and crystalline lens rise (CLR). Results There were no differences in mean age (P =0.862) and male/female ratio (P =0. 380) between the 2 groups. After surgery, AOD, TISA, ARA, ACA and ACV increased significantly (P 〈0.001-0.044), while no changes were found in ACD, ACW and CLR (P =0.102-0.609) in PI group. In Trab group, ACV increased significantly postoperation (P 〈0.001) while other parameters shown no changes. Conclusions Both surgery of PI and Trab can increase ACV; PI can improve the anterior angle parameters in APACG, but Trab surgery shows no changes of those parameters.
关 键 词:闭角型青光眼 房角结构 周边虹膜切除术 小梁切除术 前段光学相干断层扫描
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