抗心磷脂抗体阳性妇女妊娠结局  

Pregnancy outcome of the women with positive anticardiolipin antibody

作　　者：梁秀[1] 潘柏轩[2] 梁艳[1] 

机构地区：[1]深圳市福田区计划生育服务中心,518048 [2]深圳市妇幼保健院

出　　处：《中国妇幼保健》2011年第22期3457-3458,共2页Maternal and Child Health Care of China

基　　金：广东省人口和计划生育委员会科研项目〔2010316〕

摘　　要：目的：了解抗心磷脂抗体（ACA）阳性妇女的妊娠结局,为防治病理妊娠提供参考。方法：2010年7~12月进行优生健康检查的已婚未育育龄妇女428人,血清ACA采用酶联免疫吸附法（ELISA）测定;2011年3月20~21日对ACA阳性妇女进行随访。结果：一般人群已婚未育育龄妇女ACA阳性率11.45%;ACA阳性妇女3~6个月后随访,ACA阳性已孕者正常妊娠至孕晚期及足月产者占97.44%,ACA阳性未孕者新增妊娠4例,无病理妊娠。结论：ACA阳性妇女并不必然发生病理妊娠;1次检测ACA阳性无临床症状孕妇妊娠结局良好,对妊娠妇女常规作ACA检测是不必要的。Objective：To understand the pregnancy outcome of the women with positive anticardiolipin antibody（ACA）,provide reference for prevention and treatment of pathological pregnancy.Methods：428 married and childless women of childbearing age who received eugenic health examination in the hospital from July to December in 2010 were selected,the serum ACA level was detected by ELISA;the women with positive ACA were followed up from March 20th to March 21st in 2011.Results：The positive rate of serum ACA of married and childless women in the general population was 11.45%;the women with positive ACA were followed up after 3~6 months,the proportion of pregnant women with positive ACA（who continued pregnancy normally till the third trimester of pregnancy and deliveried at term） was 97.44%,among the unpregnant women with positive ACA,4 women got pregnancy,no pathological pregnancy occurred.Conclusion：The women with positive ACA are not inevitable to have pathological pregnancy;the pregnant women without clinical symptoms who are found with positive ACA for the first detection have good pregnancy outcome,regular ACA detection is not necessary for pregnant women.

关 键 词：抗心磷脂抗体 酶联免疫吸附法 妊娠结局 

分 类 号：R773[医药卫生—眼科]