308例消化性溃疡复发原因分析与防治策略  

Cause and prevention of recurrence of peptic ulcer Strategy

作　　者：艾远征 许先进 郭万锋 聂红秀 

机构地区：[1]湖北省荆门市康复医院 [2]荆门市东宝区人民医院内科,湖北荆门448000

出　　处：《中国民康医学》2011年第15期1857-1859,共3页Medical Journal of Chinese People’s Health

摘　　要：目的:探讨消化性溃疡复发的原因及其防治策略。方法:将2007年6月至2010年6月在我院确诊的所有消化性溃疡病例进行定期复查和追踪随访,随访期间和复发就诊时至少复查一次电子胃镜及14C-尿素呼气试验。对消化性溃发病与复发的相关因素进行资料汇总和回顾性分析。结果:308例最终取得完整的临床资料,其中90例(29.22%)随访期间复发,另218例(70.78%)随访期间未复发。复发组Hp检出率为68.89%,明显高于未复发组33.94%(P<0.001)。复发组服非甾体抗炎药物(NSAIDs)、吸烟、精神紧张与应激、不规范治疗和不规律饮食等溃疡复发的相关因素亦明显高于未复发组;饮酒两组之间无差异(P>0.05)。结论:消化性溃疡复发是以Hp复发为基础的多因素共同作用的结果,根除Hp,积极控制其它相关危险因素是减少溃疡复发的有效措施和重要策略。Objective：The causes of recurrence of peptic ulcer and its control strategy.Methods：To June 2007 to June 2010 in our hospital all the peptic ulcer cases.Diagnosed and followed up for regular review,treatment and relapse during follow-up review at least once a gastroscope and the 14C-urea breathe test.On the recurrence of peptic ulcer disease and other relevant factors that sheets and reviewed.Results： 308 patients eventually achieved complete clinical data.90 cases（29.22%） relapsed during follow-up,the other 218 cases（70.78%） without recurrence during follow-up.Hp recurrence rate was 68.89% group was significantly higher than that of recurrent group 33.94%（P〈0.001）.Recurrent group serving non-steroidal anti-inflammatory drugs（NSAIDs）,smoking,mental stress and stress,irregular diet therapy and irregular factors such as ulcer recurrence is also significantly higher than recurrence group;alcohol-free between the two groups Differences（P〉0.05）.Conclusions： Helicobacter pylori（Hp）recurrence of peptic ulcer recurrence is based on the result of many factors,the eradication of Hp,active control of other risk factors are effective measures to reduce ulcer recurrence and important strategy.

关 键 词：消化性溃疡 幽门螺杆菌 非甾体抗炎药物 复发 

分 类 号：R573.1[医药卫生—消化系统]