电化学治疗癌性疼痛的临床应用  

Clinical application of electrochemical therapy for cancerous pain

作　　者：权宽宏[1,2] 李国才[1,2] 罗宏伟[1,2] 

机构地区：[1]西安高新医院胸外科,陕西西安710075 [2]西安高新医院肿瘤电化学治疗科,陕西西安710075

出　　处：《现代肿瘤医学》2011年第8期1642-1644,共3页Journal of Modern Oncology

摘　　要：目的:分析2003年1月-2010年1月电化学治疗的癌性疼痛61例疗效,探讨治疗癌痛的一种有效新方法。方法:本组病例中有头颈部、胸部、消化系、妇科、骨及软组织恶性肿瘤,肿瘤分期均为4期。疼痛级别VAS分级:1级4例,2级20例,3级37例。常规麻醉下,疼痛的瘤体内设置正负电极,1-2cm相间,治疗电量每1立方厘米100库仑。全部病例治疗过程平稳,无并发症发生。结果:全部病人疼痛缓解,有效率100%。疼痛效果评估:完全缓解(CR)56例,部分缓解(PR)5例;疗效维持最短7天,最长者超过1年。治疗后均停止用吗啡、杜冷丁等镇痛药。结论:对于适应电化学治疗的癌痛患者,进行电化学治疗,方法简便、不出血、痛苦小,不仅能缓解癌痛,还能有效治疗原发肿瘤以及复发癌和转移癌,是一种有效的新方法,值得推广应用。Objective： To study the effect of electrochemical therapy（EChT） in tumor treatment from Jan,2003 to Jan,2010,in 61 cases of advanced tumor with cancerous pain.Methods：Cases in this study included malignant tumors of head-neck,chest,digestive system,gynecology,bone and soft tissues.All of tumors were classified as Ⅳ stage.Pain levels were determined according to VAS Classification,and 1,20 and 37 cases were classified in the 1st,2nd,and 3rd grade respectively.After anesthesia,anode and cathode were inserted into tumors with 1-2cm interval,and electrical quantity were set up 100 coulombs per cm3.The therapeutic courses of all patients were safe and no complication.Results： All patients＇ cancerous pain relieved,and the effective rate was 100%.Therapeutic effect of pain： Complete response（CR） was 56 cases,partial response（PR） was 5 cases;curative effect maintained 7 days at least,and the longest was over 1 year.After treatment,all patients stopped to use morphine,dolantin and other anodynes.Conclusion： The patients who suffer from cancerous pain and suit for EChT can be treated with EChT.EChT is easy to operate,no bleeding,and little pain,and it is not only to alleviate cancer pain,but also to cure primary tumor,metastatic and relapse tumor effectively,is a new and effective method for cancerous pain,and deserve to be applied.

关 键 词：恶性肿瘤 癌性疼痛 电化学治疗 

分 类 号：R730.58[医药卫生—肿瘤]