核黄素对大鼠脂质过氧化影响的研究  

The effect of riboflavin on lipid peroxidation in rats

作　　者：梁惠芳[1] 柳启沛[1] 徐京[1] 

机构地区：[1]上海医科大学公共卫生学院,上海200032

出　　处：《卫生研究》1999年第6期370-371,共2页Journal of Hygiene Research

摘　　要：为探讨核黄素对大鼠脂质过氧化的影响，采用随机区组设计，研究了不同核黄素水平对大鼠核黄素营养状况及脂质过氧化的影响。饲养６周后发现，核黄素缺乏引起大鼠全血谷胱甘肽还原酶活性系数升高及全血还原型谷胱甘肽含量降低，全血丙二醛浓度升高及红细胞超氧化物歧化酶活性降低。In order to study the effect of riboflavin on lipid peroxidation in rats, randomized block design was used to study the effect of different riboflavin levels on the riboflavin status and lipid peroxidation of S.D.rats.The rats fed with riboflavin deficient diets for 6 weeks had higher levels of BGRAC,blood malondialdehyde and lower levels of GSH than those with riboflavin sufficient diets.The RBC SOD activity is also reduced in riboflavin deficiency rats.It is concluded that riboflavin deficiency increases the extent of lipid peroxidation.

关 键 词：核黄素 BGRAC 脂质过氧化 

分 类 号：Q563.2[生物学—生物化学]