泡利芬对煤工尘肺病人肺功能的影响  

Impact of Polifen on pulmonary function in patients with coal workers pneumoconiosis

作　　者：任爱国[1] 袁聚祥[1] 

机构地区：[1]华北煤炭医学院,河北唐山063000

出　　处：《中国工业医学杂志》1999年第6期324-326,共3页Chinese Journal of Industrial Medicine

摘　　要：目的　评价泡利芬对煤工尘肺病人肺功能的改善作用。方法　选择诊断为Ⅰ或Ⅱ期的煤工尘肺病人４１９ 例作为研究对象， 按尘肺期别和病情分层， 将患者随机分为矽肺宁对照组、高剂量茶多酚组、Ｖｉｔ Ｃ 组和低剂量茶多酚组。分别测定服药前、服药３ 个月和６ 个月时的肺功能。对各指标服药３ 个月和６ 个月时与服药前的差值进行统计学检验。结果　服药３ 个月时， 服用茶多酚两组的肺活量较服药前增加。各组用力肺活量均增加。茶多酚和Ｖｉｔ Ｃ 组残气量减少， 矽肺宁组增加。服药６ 个月时， 茶多酚组的各项指标仍呈好转趋势， 而Ｖｉｔ Ｃ 组除肺活量外， 其余各指标则无好转趋势。结论　用茶多酚和数味具有理气、化痰作用的中药制成的泡利芬有改善煤工尘肺病人肺功能的作用。Objective To evaluate the effects of Polifen on pulmonary function in patients with coal workers pneumoconiosis (CWP).Methods Four hundred and nineteen patients with CWP at stages Ⅰ and Ⅱ were chosen and randomly divided into four groups,treated with Xifeining and high dose tea polyphenols for three months,and vitamin C and low dose polyphenols for six months,respectively.Pulmonary function were measured for each of them before treatment and at the end of treatment,respectively,and differences between them were tested for statistical significance.Results VC at the end of three month treatment in the two groups with tea polyphenols and FVC in all group increased,as compared with that before treatment,RV reduced in those with tea polyphenols and vitamin C and increased in that with Xifeining.All the indicators of pulmonary function appeared an improving trend in those with tea polyphenols and no such trend was found in that with vitamin C except for its VC.Conclusion Polifen,a preparation of tea polyphenols and several kinds of Chinese herbal medicine with effects on regulating the flow of vital energy and resolving phlegm,can improve their pulmonary function in patients with CWP.

关 键 词：煤工 尘肺 治疗 茶多酚 肺功能 

分 类 号：R135.2[医药卫生—劳动卫生]