SPECT/CT对脊柱病变鉴别诊断的价值  被引量:23

Clinical value of SPECT/CT in differentiating spinal diseases

在线阅读下载全文

作  者:江勇[1] 米岚[1] 余大富[1] 董学先[1] 

机构地区:[1]云南省第一人民医院核医学科,昆明650031

出  处:《中华核医学杂志》2011年第4期223-226,共4页Chinese Journal of Nuclear Medicine

摘  要:目的评价SPECT/CT显像在脊柱病变鉴别诊断中的应用价值。方法对53例^99Tc^m-MDP全身骨显像脊柱呈放射性浓聚患者进行SPECT/CT显像,获得SPECT、CT及两者的融合图像。所有病灶均以病理学诊断及6个月以上的影像学随访为最终诊断结果,计算SPECT/CT融合图像的诊断效能。结果SPECT/CT骨显像诊断骨转移肿瘤的灵敏度为96.00%(24/25),特异性为96.43%(27/28),准确性为96.23%(51/53),假阳性率为3.57%(1/28),假阴性率为4.00%(1/25),阳性预测值为96.00%(24/25),阴性预测值为96.43%(27/28)。对脊柱浓聚灶诊断非转移性骨病变的灵敏度为96.43%(27/28),特异性为96.00%(24/25),准确性为96.23%(51/53),假阳性率为4.00%(1/25),假阴性率为3.57%(1/28),阳性预测值为96.43%(27/28),阴性预测值为96.00%(24/25)。结论SPECT/CT同机融合显像结合了CT的解剖定位功能与^99Tc^m-MDP骨显像的高灵敏度,可提高诊断的特异性和准确性,有助于对脊柱病变的鉴别诊断。Objective To evaluate the value of SPECT/CT in differentiating malignancy from benign spinal disease. Methods Fifty-three patients with loci of abnormally increased uptake in the spine detected by 99Tcm-MDP planar whole body bone scan subsequently underwent bone SPECT/CT. The final diagnosis was determined by pathological examination or clinical follow-up (≥6 months), which was applied to calculate the diagnostic efficacy of bone SPECT/CT. Results A total of 25 patients were confirmed to have bone malignancy. The diagnostic sensitivity, specificity, accuracy, false positive rate, false negative rate, positive predictive value and negative predictive value for 99Tcm-MDP bone SPECT/CT were 96.00% (24/25), 96.43 % (27/28), 96.23 % (51/53 ), 3.57 % ( 1/28 ), 4.00% ( 1/25 ), 96.00% (24/25) and 96.43 % (27/28), respectively. Conclusion 99Tcm-MDP bone SPECT/CT imaging provides good clinical value for the differential diagnosis of spinal diseases.

关 键 词:脊柱疾病 肿瘤转移 体层摄影术 发射型计算机 单光子 体层摄影术 X线计算机 MDP 

分 类 号:R730.44[医药卫生—肿瘤]

 

参考文献:

正在载入数据...

 

二级参考文献:

正在载入数据...

 

耦合文献:

正在载入数据...

 

引证文献:

正在载入数据...

 

二级引证文献:

正在载入数据...

 

同被引文献:

正在载入数据...

 

相关期刊文献:

正在载入数据...

相关的主题
相关的作者对象
相关的机构对象