直肠癌前切除术后局部复发的危险因素研究及其预防  

Risk Factors Study and Prevention of Local Recurrence After Anterior Resection of Rectal Cancer

作　　者：谈凯[1] 张克亮[1] 

机构地区：[1]湖北省肿瘤医院胃肠泌尿外科,湖北武汉430079

出　　处：《实用预防医学》2011年第8期1506-1507,共2页Practical Preventive Medicine

摘　　要：目的分析直肠癌患者前切除术后局部复发的危险因素并探讨有效的预防措施。方法选择2007年10月-2010年1月湖北省肿瘤医院行直肠癌前切除术的98例患者,统计术后局部复发比例,分析复发的危险因素。结果本组98例患者的术后局部复发率为11.2%(11/98),其发生与性别、年龄、肿瘤距肛缘距离、全系膜切除、辅助化疗、病理分型恶性程度及Duck’s分期相关(P<0.05)。结论临床工作者应了解直肠癌前切除术后局部复发的危险因素,注意针对危险因素采取相应的预防措施,降低患者术后局部复发率,提高患者的生活质量。Objective To analyze the risk factors of local recurrence after anterior resection of rectal cancer,and to explore the effective preventive measures.Methods Ninety-eight rectal cancer patients undergoing anterior resection in Hubei Tumor Hospital from October 2007 to January 2010 were selected.The proportion of local recurrence and the risk factors for recurrence were analyzed.Results The local recurrence rate of 98 patients in this group was 11.2%（11/98）,and the local occurrence was correlated with sex,age,tumor distance from the anal margin,total mesorectal excision,adjuvant chemotherapy,pathologic type,the degree of malignancy and Duck＇s staging（P0.05）.Conclusions Clinicians should be aware of the risk factors of local recurrence after anterior resection of rectal cancer and take appropriate preventive measures for the risk factors so as to reduce the postoperative local recurrence rate and improve the patient＇s quality of life.

关 键 词：直肠癌 前切除术 局部复发 危险因素 预防 

分 类 号：R735.37[医药卫生—肿瘤]