无溶剂条件下硅胶固载磷酸催化环己酮与芳香醛的缩合反应  

Cross-aldol condensation between cyclohexanone and aromatic aldehydes catalyzed by silicon dioxide supported phosphoric acid under solvent-free conditions

作　　者：裴强[1] 金春雪[1] 薛灵芬[1] 张小宁[1] 宋文姬[1] 

机构地区：[1]信阳师范学院化学化工学院,河南信阳464000

出　　处：《化学研究与应用》2011年第8期1083-1086,共4页Chemical Research and Application

基　　金：教育部科学技术研究重点项目(210129)资助;信阳师范学院青年教师基金资助项目(200933)

摘　　要：以硅胶(mSiO2·nH2O)固载磷酸为催化剂,在无溶剂条件下催化环己酮与芳香醛的Cross-Aldol缩合反应,得到7个相应的α,β-不饱和羰基化合物,反应时间短(60～150 min),产率高(73.4%～92.7%)。该方法操作简单,催化剂可重复使用,且对环境友好。Seven α,β-unsaturated ketones were synthesized from cross-aldol condensation between aromatic aldehydes and cyclohexanone in the presence of silicon dioxide supported phosphoric acid under solvent-free conditions.It showed advantages of short reaction time（60～150 min） and good yields（73.4%～92.7%）.This method was simple,fast,environmental friendly,and the catalyst could be reused.

关 键 词：无溶剂 Cross-Aldol缩合 硅胶 磷酸 

分 类 号：O621.3[理学—有机化学]