老年原发性青光眼低对比度视力与HRT-Ⅱ视盘参数的相关性  

Correlation between low contrast visual acuity and optic disc parameters measured with HRT-Ⅱin the aged population with primary glaucoma

作　　者：李颖[1] 王敏[1] 刘梅[2] 靳传红[1] 吴欣怡[2] 

机构地区：[1]山东大学齐鲁医院老年病科,济南250012 [2]山东大学齐鲁医院眼科,济南250012

出　　处：《山东大学学报（医学版）》2011年第8期79-83,共5页Journal of Shandong University:Health Sciences

摘　　要：目的研究老年原发性青光眼低对比度视力的变化特点及与海德堡视网膜断层成像仪Ⅱ型(HRT-Ⅱ)颞侧盘沿参数的相关性。方法选择老年原发性青光眼患者45例(83眼),根据视野结果分为早期组21例(40眼)和中晚期组24例(43眼);正常对照组23例(40眼)。对3组受试者行屈光矫正后,采用多功能视力测量仪测得100%、25%、10%和5%4个对比度视力,分析比较各组低对比度视力有无统计学差异及青光眼组各低对比度视力与HRT-Ⅱ测得的颞侧盘沿面积(RA)、盘沿容积(RV)有无相关性。结果 3组间25%、10%及5%对比度视力总体比较差异有统计学意义(P<0.05);早期组与正常对照组各低对比度视力比较差异无统计学意义(P>0.05);中晚期组各低对比度视力较正常对照组和早期组均下降(P<0.05),10%、5%低对比度视力与颞侧RA呈负相关(r=-0.361;r=-0.318,P均<0.05)、与颞侧RV呈负相关(r=-0.303;r=-0.377,P均<0.05)。结论老年原发性青光眼病情进展导致低对比度视力下降,中晚期患者10%、5%低对比度视力与颞侧盘沿参数RA、RV有相关性,对比度视力检查可以对老年中晚期青光眼中心视功能的病情评估和监测提供依据。Abstract： Objective To investigate changes of low contrast visual acuity and its correlation with temporal optic disc parameters of the neuroretinal rim measured with Heidelberg retinatomography （ HRT- Ⅱ ） in the aged population with primary glaucoma. Methods 83 eyes from 45 patients with primary glaucoma and 40 eyes from 23 healthy subjects were examined with HRT- Ⅱ for optic disc parameters of the rim area（RA） and rim volume（RV） . Their corrected vis- ual acuity at 100%, 25%, 10% and 5% contrast levels in bright background were measured with a multi-functional vis- ual acuity analyzer. According to the mean defect （MD） of visual field, glaucomatous patients were divided into the early glaucoma group （21 cases, 40 eyes） and the moderate and severe glaucoma group （24 cases, 43 eyes）. Corrected visual acuity at 25%, 10% and 5% contrast levels was compared among the normal group and the two glaucomatous groups. Correlations were evaluated between corrected visual acuity at the three low contrast levels and the temporal disc parameters of RA and RV in each glancomatous group. Results There were statistical differences in corrected visual acuity at 25%, 10% and 5% contrast levels among the three groups（P 〈0.05）. Corrected visual acuity at three low contrast levels in both the normal group and the early glaucoma group were significantly better than in the moderate andsevere glaucoma group （ P 〈 0.05 ）. There was no statistical difference between the early glaucoma group and the normal group（P 〉0.05 ）. Corrected visual acuity at 10% and 5% contrast levels in the moderate and severe glaucoma group was negatively correlated with temporal R.A（ r = - 0. 361 ; r = - 0. 318, P 〈 0.05 ） and RV （ r = - 0. 303 ; r = - 0. 377, P 〈 0.05）. Conclusions Visual acuity at low contrast levels declines in the aged population with advanced pri- mary glaucoma. In moderate and severe glaucomatous patients, visual acuity at 10% and 5% contrast levels is correlated with temporal opt

关 键 词：青光眼 低对比度视力 海德堡视网膜断层成像仪Ⅱ型(HRT一Ⅱ) 

分 类 号：R775.2[医药卫生—眼科]