29例非功能性胰岛细胞瘤的外科诊治  

Diagnosis and surgical treatment of nonfunctioning islet cell tumors:a report of 29 cases

作　　者：王宪伟[1] 龙学颖[2] 曾镇 李宜雄[1] 

机构地区：[1]中南大学附属湘雅医院普通外科,湖南长沙410008 [2]中南大学附属湘雅医院放射科,湖南长沙410008 [3]湖南省旺旺医院普通外科,湖南长沙410016

出　　处：《中国普通外科杂志》2011年第8期861-863,共3页China Journal of General Surgery

摘　　要：目的探讨无功能胰岛细胞瘤的诊断治疗。方法对近17年间湘雅医院收治的29例无功能胰岛细胞瘤患者的临床资料进行回顾性分析。结果 29例患者均无明显临床症状,最常见的临床体征为腹部包块(25/29)。B超和CT为最常用的术前检查手段,其阳性率分别为100%(29/29)和96.5%(28/29)。其中良性占65.5%(19/29),恶性占34.5%(10/29)。手术切除率为100%。结论无功能胰岛细胞瘤症状缺乏特异性,B超及CT应为首选的检查方法。包膜不完整和浸润性生长者可确诊为恶性,外科手术是首选方法,疗效优于胰腺外分泌肿瘤。Objective To investigate the diagnosis and treatment of nonfunctioning islet cell tumor（NICT）. Methods The clinical data of 29 NICT patients treated at Xiangya Hospital in the past 17 years were retrospectively analyzed. Results In the 29 cases,who all had no obvious clinical symptoms,the major sign was abdominal mass（25/29）.B-type ultrasound and CT examination were the main approaches of preoperative detecion,and the detection rate was 100%（29/29） and 96.5%（28/29）,respectively.Of these patients,benign and malignant lesions accounted for 65.5%（19/29） and 34.5%（10/29）,respectively.The surgical resection rate was 100%. Conclusions NICT has no typical clinical symptoms and B-type ultrasound and CT are effective detection methods.It can be diagnosed as malignant tumor,if the lesion lacks an intact capsule or shows aggressive growth.Surgery is the first option to treat NICT,and the treatment results of the NICT patients are better than those patients with exocrine tumor of pancreas.

关 键 词：无功能胰岛细胞瘤/诊断 无功能胰岛细胞瘤/外科学 

分 类 号：R736.7[医药卫生—肿瘤]