多发性骨髓瘤中医证型聚类分析研究  

Cluster Analysis Research of Patterns of TCM Syndrome in Multiple Myeloma

作　　者：黄智莉[1] 陈志雄[2] 于天启[2] 戴媺[1] 杨宏光[1] 聂树林[3] 

机构地区：[1]广东省广州市中医医院 [2]广州中医药大学第三附属医院 [3]华南理工大学

出　　处：《山西中医》2011年第8期41-43,共3页Shanxi Journal of Traditional Chinese Medicine

基　　金：广州市卫生局课题(编号:2010A10)

摘　　要：目的:对多发性骨髓瘤中医辨证分型规律进行探讨,为中医建立和完善多发性骨髓瘤(MM)的规范化辨证治疗体系提供依据。方法:选取初诊的128例MM患者的临床资料进行分析,录入证候四诊信息,运用聚类分析的方法,观察中医证型分布情况。结果:初诊MM的临床中医证型分为脾肾两虚、脾肾阳虚、脾肾阴虚、水湿内蕴、痰毒瘀阻五种类型,提示MM病机以脾肾虚为主,以痰瘀湿毒为要。结论:聚类分析应用于中医证候研究能较为准确地反映临床实际。Objective ： To investigate the regular patterns of TCM syndromes in Multiple myeloma, and provide the basis for the establishment and improvement of standardization of MM in TCM Differential Treatment system. Methods： 128 patients newly diagnosed MM were chosen, and their clinical data were analyzed. Their four diagnostic information was recorded, and cluster analysis method was applied to do the observation of the distribution of syndromes. Results ： The regular patterns of TCM syndrome in Multiple myeloma were following, spleen and kidney deficiency, Yang deficiency of spleen and kidney, Yin deficiency of spleen and kidney, intrinsic moisture in body, and phlegm,toxin and stasis obstruction. This suggested that spleen deficiency is the main pathogenesis in MM, and phlegm, toxin and stasis are the important factors in onset. Conclusion ： Application of Cluster analysis can reflect clinical practice more accurately in TCM research.

关 键 词：多发性骨髓瘤 中医证型 聚类分析 临床研究 

分 类 号：R733.3[医药卫生—肿瘤]